Correlation between Objective SCORAD and Three-Item Severity Score Used by Physicians and Objective PO-SCORAD Used by Parents/Patients in Children with Atopic Dermatitis
Abstract:Background: A self-assessment rating scale (SAS) is a good tool to assess the fluctuating disease severity and quality of life (QoL) in children with atopic dermatitis (AD). The European Task Force on Atopic Dermatitis created an SAS based on the Scoring Atopic Dermatitis (SCORAD) index, called the Patient-Oriented SCORAD (PO-SCORAD). Objective: The aim of our study was to measure the correlation between alternative systems such as the Objective SCORAD, the Three-Item Severity (TIS) score and the Objective PO-… Show more
“…who proposed a new self‐assessment tool, evaluating the burden of AD before and after treatment, which showed promise by being correlated with disease severity. The similar correlations between self‐reported and healthcare professional‐assessed measures of disease activity found in our study supports the suggestion by Oosterhout et al . comparing SCORAD to PO‐SCORAD, reporting a positive correlation ( r = 0.63, P < 0.001), as well as Baron et al .…”
AD impacts negatively on the QoL, proportional to the severity of the disease. Furthermore, female sex and facial eczema are associated with low QoL. Positive FLG null mutation status is not associated with QoL or disease severity.
“…who proposed a new self‐assessment tool, evaluating the burden of AD before and after treatment, which showed promise by being correlated with disease severity. The similar correlations between self‐reported and healthcare professional‐assessed measures of disease activity found in our study supports the suggestion by Oosterhout et al . comparing SCORAD to PO‐SCORAD, reporting a positive correlation ( r = 0.63, P < 0.001), as well as Baron et al .…”
AD impacts negatively on the QoL, proportional to the severity of the disease. Furthermore, female sex and facial eczema are associated with low QoL. Positive FLG null mutation status is not associated with QoL or disease severity.
“…3b). However, the appraisement of the symptom sleeplessness by the parents differs between PO-SCORAD and SCORAD in the present study [22]. The sleeplessness score was significantly reduced (fig.…”
Section: Discussioncontrasting
confidence: 53%
“…The Patient-Oriented SCORing Atopic Dermatitis (PO-SCORAD) represents a self-assessment score to involve parents in effective skin monitoring [13,18]. Sharing a comparable analytic factor as the SCORAD, the PO-SCORAD facilitates the communication between parents and physicians [19,20,21,22]. …”
Background: Dry skin is a common skin condition in childhood. Few studies exist investigating the influence of daily skin care on dry skin in infants at risk of developing atopic dermatitis (AD). We aimed to assess the effect of skin care on dry skin in this special cohort using validated scores for AD and analysis of skin microtopography. Methods: 43 children were randomized to group 1 (G1) and group 2 (G2) and 22 infants to group 3 (G3). During 16 weeks, G1 and G3 applied daily a plant-based emollient and G2 a petrolatum-based emollient. The core outcome was assessed by Severity Scoring of Atopic Dermatitis (SCORAD) and Patient-Oriented SCORing Atopic Dermatitis (PO-SCORAD). The influence on the parents' life was evaluated by a questionnaire and microtopography by Visioscan® VC 98. Results: The SCORAD index declined significantly until week (W) 16 in all groups (p ≤ 0.041). The sleeplessness score analyzed by PO-SCORAD was highly reduced after W12 in G1 and after W16 in G2 (p ≤ 0.030). The influence on the parents' anxiety was reduced in G3 at W12 and W16 (p = 0.016). The Visioscan parameter scaliness strongly diminished at W4 (p ≤ 0.049) and W16 (p ≤ 0.013) in all groups. Conclusions: This trial demonstrates improved skin conditions and sleep following daily emollient application in infants and children having dry skin and being at risk of AD. Especially parents of infants showed a reduced fear that their children might develop AD. Further studies are required to investigate the preventive effect of daily emollient therapy in this special cohort evaluating the outcome measures used in this trial.
“…The severity of AD was assessed both by the physician and by the participant and there were no significant differences at the first examination either in the intervention or in the control group. Previous studies have shown that assessments of disease severity both by the physician and by the participants (caregivers) tend to be similar …”
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.