correlation between the levels of anti-sperm antibodies and some cytokines in the seminal plasma with sperm parameters and leukocytes concentration of infertile men

Abstract

Background: The aim of this work is study the relationship between sperm parameters, anti-sperm antibody and some cytokines levels for infertile men. Semen samples were studied for 88 infertile men;of these (28) infertile men with normozoospermic, (29) with oligozoospermic and (31) with asthenozoospermic ,samples were collected from Fertility Centre in Al-Sadder teaching hospital in Al-Najaf / Iraq during the period of (2/11/ 2021) and (5/2/2022). All participants underwent seminal analysis and measurement of seminal plasma antisperm antibody and some cytokine. The result of the study showed negative correlation between antisperm antibody and of interleukin (IL-1and IL-6) with sperm parameter and posative correlation with leucocytes. The presence of leucocytes in the semen is associated with an increase in levels of interleukin (IL-1and IL-6) in the seminal plasma of infertile men. The presence of antisperm antibody and interleukin (IL-1and IL-6) in the seminal plasma is associated with a negative relationship in the semen quality of infertile men.