Objectives:The aim of this study was to investigate the effects of face mask usage on the sleep quality of patients with nasal septal deviation. Material and Method: Thirty-four patients with unilateral nasal septum deviation (Group 1) and 27 healthy subjects without septum deviation (Group 2, control) were included in the study. Mask usage time per day (hours) in the last week, weight, length and BMI values, smoking, and alcohol habits were asked. In both groups, the sleep quality of the patients was evaluated by Mini Sleep Questionnaire (MSQ). Sleep delay (SD), sleep awakenings (SA), sleep medications (SM), daytime sleep (DS), morning fatigue (MF), habitual snoring (HS), morning awakening (MA), morning headache (MH), chronic fatigue (CF), and restless sleep (RS); and total MSQ items were evaluated. Results: All subjects used surgical masks. In the nasal septal deviation group, the right-sided deviation was detected in 15 (44.1%) patients and left-sided deviation was detected in 19 (55.9%) patients. Deviation located was anterior deviation in 12 (35.3%) patients, posterior deviation in 13 (38.2%) patients and antero-posterior deviation in 9 (26.5%) patients. Sleep Medications (SM) and Morning Headache (MH) values of the deviation group (Group 1) were significantly lower than those in the control group (p<0.05). There was no difference between other MSQ items and total MSQ score of the septal deviation and control groups (p>0.05). In older patients with septal deviation, Sleep Awakenings (SA), Habitual Snoring (HS), Morning Awakening (MA), and Total MSQ scores increased (p<0.05) Conclusion: Facial mask usage did not cause sleep disorders in patients with nasal septal deviation. However, aging may cause disturbed sleep quality.