Correlation of Pap smear and colposcopic finding with directed biopsy in detection of cervical neoplasm

Abstract

Introduction: Cancer of uterine cervix is the most common genital tract malignancy. Pap smear though widely used screening test for cervical cancer has the disadvantage of low sensitivity. Colposcopy has higher sensitivity compared to Pap smear. Concurrent screening with Pap smear and colposcopy can overcome this problem. Aim: The aim of the study was correlation of Pap smear and colposcopic finding with directed biopsy in detection of cervical neoplasm. Methods: The Present study was conducted in the

Comparison of Colposcopy and Histopathology in Abnormal Cervix

“…Mazihah et al reported an accuracy rate of 94% [ 21 ], and Ashmita et al reported 86.54% [ 22 ]. Compared to our study, Mazihah et al [ 21 ] and Upadhyay et al [ 11 ] had higher sensitivity, and Savitha et al [ 15 ] and Ashmita et al [ 22 ] had lower values. Although the primary purpose of colposcopy is to determine where to perform a biopsy, it also helps to improve the identification of intraepithelial lesions.…”

“…Savitha et al also observed that white discharge per vagina was the most common symptom (86%) among cases [ 15 ]. Similar findings were reported by Upadhyay et al [ 11 ], Chaudhary et al [ 16 ], and Bhalerao et al [ 17 ]. Most of the patients had findings of inflammation (47%) followed by acetowhite areas (13%).…”

“…In a study on the evaluation of an unhealthy cervix, Gohil et al observed that most patients (53.33%) were over 40 years [ 10 ]. Similar results were found in studies by Upadhyay et al [ 11 ] and Joshi et al [ 12 ], in which the mean age of patients was 36.4 and 32.2 years, respectively. Other studies by Pimple et al [ 13 ] and Boicea et al [ 14 ] have reported similar patient distributions.…”

“…Savitha et al reported that the sensitivity and specificity of colposcopy were 85% and 83.75%, respectively [ 15 ]. Upadhyay et al reported that the sensitivity and specificity of colposcopy were 94.1% and 87.8%, respectively [ 11 ]. Mazihah et al reported an accuracy rate of 94% [ 21 ], and Ashmita et al reported 86.54% [ 22 ].…”

Correlation of Pap Smear and Colposcopic Finding With Directed Biopsy to Assess the Advantage of Concurrent Testing by Cytology and Colposcopy in the Detection of Cervical Neoplasm

“…Colposcopic directed biopsies of suspicious area provide the final confirmation of diagnosis in most of the situations. 10 It is used to determine the biopsy site in women who have abnormal Pap test results and, in an effort to increase the accuracy of colposcopic diagnosis and facilitate communication. It has predominately been used for identifying the biopsy site for secondary histological diagnosis when abnormal Pap results are found.…”