Correlation of s-IgA and IL-6 Salivary with Caries Disease and Oral Hygiene Parameters in Children

G, Lo Giudice; Nicita, Fabiana; Militi, Angela; Bertino, Rossella; Matarese, Marco; Currò, Monica; Damiano, Carmelo Salpietro; Mannucci, Carmen; Calapai, Gioacchino

doi:10.3390/dj8010003

Cited by 26 publications

(32 citation statements)

References 29 publications

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“…Bartold and Haynes reported higher IL-6 levels in inflamed gingival tissues compared to healthy control tissues [28]. Lo Giudice et al reported that a high level of IL-6 is present when caries is in an active state and associated to infectious consequences [6].…”

Section: Resultsmentioning

confidence: 99%

“…The correlation between oral hygiene, gingival inflammation, and inflammatory response has been largely described [ 14 , 15 , 16 , 17 ]. Optimal values of performance hygiene index are significantly related to absence of gingival pathology and caries [ 6 ].…”

Section: Discussionmentioning

confidence: 99%

“…The variation in IL-6 levels in different oral diseases has already been evaluated; inflammatory diseases such as periodontitis and oral lichen planus can induce an increase in cytokines levels [5]. Tooth decay, especially in active state, can induce a significant increase in crevicular fluid IL-6 levels in children [6].…”

Section: Introductionmentioning

confidence: 99%

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Correlation between Oral Hygiene and IL-6 in Children

et al. 2020

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The aim of this study was to evaluate the correlation between marginal gingivitis, oral hygiene parameters, and interleukin-6 (IL-6) levels in gingival crevicular fluid of 40 children. The marginal periodontal pathology was evaluated by gingival index (GI). The status of oral hygiene was estimated by using patient hygiene performance (PHP), brushing frequency (BF), and plaque index (PI). IL-6 levels in gingival crevicular fluid were measured to evaluate the inflammation in marginal gingiva. PHP score showed a significant correlation with GI, BF, and PI. The groups based on PHP ranges were significantly related to IL-6 concentration in crevicular fluid.

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Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Correlation between Oral Hygiene and IL-6 in Children

et al. 2020

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“…In these cases, clinicians may be forced to reach a presumptive diagnosis and make treatment decisions during the interventions [ 17 ]. Lo Giudice et al affirmed that the diagnostic phase could be improved by measuring IL-6 in saliva because the levels were significantly higher in children with active caries than in children without caries [ 18 ]. New instruments such as intraoral scanners and CAD-CAM technologies have improved the clinical phase of treatment, such as through the intraoperative performance of a crown or inlay [ 19 ].…”

Section: Discussionmentioning

confidence: 99%

Dental Treatments under General Anesthesia on Children with Special Health Care Needs Enrolled in the Spanish Dental Care Program

Pecci-Lloret

Guerrero‐Gironés

López-González

et al. 2021

JCM

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The purpose is to analyze the medical characteristics of children with special health care needs (CSHCN) recommended for dental treatment under general anesthesia (GA), postoperative complications, and dental treatment outcomes under the regulation of the Spanish Dental Care Program (PADI). 111 clinical records were selected. The study population was divided into three age groups. The quantitative data was specified as the mean ± SD. For the qualitative variables, the Chi-Square test was used. One-way ANOVA and Bonferroni tests were used to examine the effect of the “age group” and the number of treatment procedures. A total of 1473 treatment procedures were performed, of which 110 (7.5%) were cleanings, 898 (61%) were restorative procedures, 332 (21.7%) were extractions, 22 (1.6%) were endodontic treatments, 62 (4.2%) were pulpotomies, and 59 (4%) were stainless steel crowns. Regarding the mean number of incisor root canal treatments (RCT), age group 3 received a significantly higher mean number of incisor RCTs than age group 1 (p = 0.02). Age group 1 received a higher average of pulpotomies and stainless-steel crowns (p = 0.00) compared to groups 2 and 3. GA is a safe procedure for the dental treatment of CSHCN, with minimal postoperative complications, which should be included among dental public programs.

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“…Motivational apps, for example, may inspire patients to approach oral home-care measures in ways unreached to date. In dentistry, periodontitis, gingivitis and caries are the most frequent bacteria-based diseases [ 12 ], in the case of caries, a correlation between salivary inflammatory cytokines, such as interleukin (IL-6) were found [ 13 ]. Both are preventable and, in the case of gingivitis, reversible, through proper home care.…”

Section: Introductionmentioning

confidence: 99%

Treatment Success and User-Friendliness of An Electric Toothbrush App: A Pilot Study

et al. 2020

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Electronic and mobile health (eHealth/mHealth) are rapidly growing areas in medicine and digital technologies are gaining importance. In dentistry, digitalization is also an emerging topic, whereby more and more applications are being offered. As an example, using real-time feedback, digital application software (an app) was designed to help users brush their teeth more accurately. However, there is no data on the effectiveness and haptic of such apps. Therefore, a single-blinded, randomized controlled clinical trial was designed: twenty volunteers received an electric toothbrush with an associated app to assess whether the app-assisted toothbrushing is better than without. After a short period of familiarization with the electric toothbrush, plaque index (O‘Leary et al. 1972) was recorded and subjects were assigned to the test (with app; n = 10) or the control group (no app; n = 10). At the end of the 2-week pilot study period, plaque was again assessed and participants in the test group completed a questionnaire about the app’s user-friendliness. Statistical analysis revealed no significant differences between the test and control groups. The plaque index improved on average by 8.5% points in the test and 4.7% points in the control group. Fifty percent of the test group participants were of the opinion that they had achieved better cleaning results and would recommend the app to others, although the app contributed only marginally to increased plaque removal. However, such apps may nevertheless be helpful as motivational tools, especially when tracking and monitoring cleaning data. Therefore, more development and research on this topic is indicated.

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Correlation of s-IgA and IL-6 Salivary with Caries Disease and Oral Hygiene Parameters in Children

Cited by 26 publications

References 29 publications

Correlation between Oral Hygiene and IL-6 in Children

Correlation between Oral Hygiene and IL-6 in Children

Dental Treatments under General Anesthesia on Children with Special Health Care Needs Enrolled in the Spanish Dental Care Program

Treatment Success and User-Friendliness of An Electric Toothbrush App: A Pilot Study

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