Correlation of splenic volume with hematological parameters, splenic vein diameter, portal pressure and grade of varices in extrahepatic portal vein obstruction in children

Abstract

Splenic volume has a weak correlation with splenic vein diameter, but does not correlate with portal pressure or the grade of varix. Splenic vein diameter has a statistically significant correlation with the percentage of portal pressure reduction following a leino-renal shunt. There is a statistically significant negative correlation between the splenic volume and the total leukocyte count.

Association of splenic MR elastographic findings with gastroesophageal varices in patients with chronic liver disease

“…A recent study showed that spleen volume combined with a biochemical marker (eg, platelet count and/or albumin) can predict the presence of varices in patients with CLD . Meanwhile, in pediatric patients with extrahepatic portal vein obstruction, spleen volume does not correlate with the grade of varices . We speculate that spleen volume will increase with PH development; however, it might not be useful by itself for the assessment of severe GEVs.…”

A non‐invasive magnetic resonance imaging‐based model predicts portal venous pressure

“…Intraoperative PVP measurement PVP was measured during total anesthetized surgery by inserting a polyvinyl chloride catheter into the main portal vein through the right gastroepiploic vein. [28][29][30] By connecting a pressure transducer to the catheter with the external zero reference set at the midaxillary line, PVP level was shown on the monitor (IntelliVue MP60; Philips Medical Systems) and recorded 30 s later after stabilization. Portal hypertension was defined as a PVP level of over 15 mmHg.…”

Splenic volume and hematological parameters in extrahepatic portal vein obstruction

“…Editor, I read the recent publication on correlation of splenic volume with hematological parameters, splenic vein diameter, portal pressure and grade of varices in extrahepatic portal vein obstruction with a great interest [1]. Singh et al [1] found that ''larger splenic volumes were associated with lower hemoglobin and platelet counts and significantly lower total leukocyte counts.''…”

“…Singh et al [1] found that ''larger splenic volumes were associated with lower hemoglobin and platelet counts and significantly lower total leukocyte counts.'' I agree with the finding but I would like to draw attention to some facts.…”