Correlation of Vitamin B12 and D with Neurocognitive Function in HIV/AIDS Patients in H. Adam Malik General Hospital Medan

Abstract

Objective: To analyze the correlation between levels of vitamins B12 and D with neurocognitive function in HIV/AIDS patients who are outpatients at the PUSYANSUS polyclinic, H. Adam Malik General Hospital Medan. Method: Data were analyzed using Shapiro-Wilk test statistics to evaluate the normality distribution of numerical variables, Pearson correlation test if data were normally distributed or Spearman correlation test if data were not normally distributed. Results: From the research subjects were 30 people, it was found that the majority of respondents were 17 women, with the most education status being SMA 14 people. The mean age of the patients was 34.8 6.86 years, with the median BMI of respondents being 25.2 kg/m2. Vitamin B12 levels had a median value of 511.5 ng/mL, where the majority of respondents had normal levels of 25 people. Neurocognitive function has a median score for the MMSE is 28.5, with the majority of respondents showing a normal score of 27 people. Otherwise, the mean MoCA-Ina score was 24.17 4.28, with the majority of respondents showing an abnormal score of 18 people. Conclusion: There was no significant correlation between vitamin B12 and D levels with neurocognitive function based on MMSE and MoCA-Ina scores (p>0.05) in HIV/AIDS patients. Keywords: HIV/AIDS, vitamin B12, vitamin D, neurocognitive function, MMSE, MoCA-Ina