Correlation of White Blood Cell, Neutrophils, and Hemoglobin with Metabolic Syndrome and Its Components

Li, Nan; Liu, Chenbing; Luo, Quan; Zhang, Han; Di, Sheng; Liu, Zhong

doi:10.2147/dmso.s408081

Cited by 3 publications

(1 citation statement)

References 39 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, they compared thousands of probands, and the between-group means differed by 2 × 10 9 /L and 3 × 10 9 /L, respectively, yielding an effect size (Cohen's d) of 0.05 and 0.03. In another large study on Chinese by Li et al [66], no significant differences between the groups with and without MetS were revealed. While the overall trend in platelet counts across groups with an increasing number of MetS components was significant, the location of differences was random.…”

Section: Discussionmentioning

confidence: 87%

Association of Leukocyte, Erythrocyte, and Platelet Counts with Metabolic Syndrome and Its Components in Young Individuals without Overt Signs of Inflammation: A Cross-Sectional Study

Šebeková,

Gurecká,

Podracká

2024

Children

View full text Add to dashboard Cite

The presence of metabolic syndrome (MetS) increases the risk of developing type 2 diabetes, cardiovascular diseases, and mortality. MetS is associated with increased leukocyte or erythrocyte counts. In 16- to 20-year-old males (n = 1188) and females (n = 1231) without signs of overt inflammation, we studied whether the presence of MetS and its components results in elevated blood cell counts. The leukocyte, erythrocyte, and thrombocyte counts significantly but weakly correlated with the continuous MetS score, MetS components, uric acid, and C-reactive protein levels both in males (r = −0.09 to 0.2; p < 0.01) and females (r = −0.08 to 0.2; p < 0.05). Subjects with MetS had higher leukocyte (males: 6.2 ± 1.3 vs. 6.9 ± 1.2 × 109/L; females 6.6 ± 1.5 vs. 7.5 ± 1.6 × 109/L; p < 0.001), erythrocyte (males: 5.1 ± 0.3 vs. 5.3 ± 0.3 × 1012/L; females: 4.5 ± 0.3 vs. 4.8 ± 0.3 × 1012/L; p < 0.001), and platelet counts (males: 245 ± 48 vs. 261 ± 47 × 109/L; females: 274 ± 56 vs. 288 ± 74 × 109/L; p < 0.05) than those without MetS. With the exception of platelet counts in females, the blood counts increased with the number of manifested MetS components. Phenotypes with the highest average leukocyte, erythrocyte, or platelet counts differed between sexes, and their prevalence was low (males: 0.3% to 3.9%; females: 1.2% to 2.7%). Whether functional changes in blood elements accompany MetS and whether the increase in blood counts within the reference ranges represents a risk for future manifestation of cardiometabolic diseases remain unanswered.

show abstract

Section: Discussionmentioning

confidence: 87%

Association of Leukocyte, Erythrocyte, and Platelet Counts with Metabolic Syndrome and Its Components in Young Individuals without Overt Signs of Inflammation: A Cross-Sectional Study

Šebeková,

Gurecká,

Podracká

2024

Children

View full text Add to dashboard Cite

show abstract

Association Between the Neutrophil-to-Lymphocyte Ratio and in-Stent Neoatherosclerosis and Plaque Vulnerability: An Optical Coherence Tomography Study

Gu,

Chen,

Wang

et al. 2024

Journal of Cardiovascular Pharmacology

View full text Add to dashboard Cite

This study aimed to explore the relationship between in-stent neoatherosclerosis (ISNA) and the neutrophil-to-lymphocyte ratio (NLR) in patients with in-stent restenosis (ISR) following drug-eluting stent (DES) implantation. We divided 216 patients into three groups based on the NLR tertile. We performed a comparative analysis of baseline, angiographic, and features of optical coherence tomography (OCT) between the NLR groups and performed univariate and multivariate logistic regression analyses to assess the association of the NLR with ISNA and in-stent thin-cap fibroatheroma (TCFA). Patients in the third tertile NLR group had a higher incidence of ISNA and in-stent TCFA compared with those in the first tertile. Multivariate logistic regression analysis showed that the hazard ratios and 95% confidence intervals for ISNA and TCFA were 2.673 (1.257–5.684; P=0.038) and 4.272 (1.740–10.488; P=0.004), respectively, for patients in the highest tertile compared with those in the lowest tertile. Our study showed that an increased NLR was associated with ISNA and in-stent plaque fragility in patients with ISR following DES implantation.

show abstract

Association between metabolic syndrome and hematological alterations: a review of the literature

MARTÍNEZ,

ROJAS GONZÁLEZ,

NIEVA-POSSO

et al. 2024

Riv Ital Med Lab

View full text Add to dashboard Cite

Correlation of White Blood Cell, Neutrophils, and Hemoglobin with Metabolic Syndrome and Its Components

Cited by 3 publications

References 39 publications

Association of Leukocyte, Erythrocyte, and Platelet Counts with Metabolic Syndrome and Its Components in Young Individuals without Overt Signs of Inflammation: A Cross-Sectional Study

Association of Leukocyte, Erythrocyte, and Platelet Counts with Metabolic Syndrome and Its Components in Young Individuals without Overt Signs of Inflammation: A Cross-Sectional Study

Association Between the Neutrophil-to-Lymphocyte Ratio and in-Stent Neoatherosclerosis and Plaque Vulnerability: An Optical Coherence Tomography Study

Association between metabolic syndrome and hematological alterations: a review of the literature

Contact Info

Product

Resources

About