Correlations between Serum Trace Elements (Selenium, Copper and Zinc) and Antioxidant Vitamins (Vitamin A, E and C) in Clinically Healthy Dromedary Camels

Pourjafar, Mehrdad; Badiei, Khalil; Nazifi, Saeed; Chalmeh, Aliasghar; Setayesh, Azin; Naghib, Mojtaba

doi:10.16988/iuvfd.00610

Cited by 4 publications

(4 citation statements)

References 16 publications

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“…A significant increase was also observed throughout the lactation ranging from 96 ± 3 in the early period to 130 ± 2 µg/100 mL in the last period [ 85 ]. Similar contradictory results were reported regarding the age effect [ 61 , 84 , 86 , 87 ]. Few studies exist describing plasma copper changes in camel calves post-partum.…”

Section: Trace Mineral Status In Camel Bloodsupporting

confidence: 76%

Blood Trace Element Status in Camels: A Review

Abdelrahman

Alhidary

Aljumaah

et al. 2022

Animals

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Trace minerals play an important role in animal health and productivity. They are involved also in many physiological activities, and their deficiency causes a variety of pathological problems and metabolic defects, reducing consequently the animal productivity. The demand for animal products in semi-arid areas is rapidly increasing, and the supply is still below the required level, partially due to low animal productivity. Camels (Camelus dromedarius and Camelus bactrianus) are considered one of the main sources of healthy, high-quality meat and milk for human consumption within most of the countries in the semi-arid regions. Despite their efficient adaptation to their environment, camels can suffer from the growth retardation of newborns, low feed efficiency, anemia, poor fertility, poor reproduction and many other metabolic disorders. It is well known that trace mineral deficiencies and trace mineral toxicities can influence camels’ production and reproductive efficiency, as well as many aspects of their growth and metabolism. Evaluating the trace minerals status of camels and their variability is an obvious step toward improving camels’ productivity and health. Thus, the present article reviews the data regarding the status of trace minerals (copper, zinc, iron, selenium, manganese, cobalt, iodine, fluorine, molybdenum, sulfur, bromide and nickel) in camel blood and their physiological variability, with a focus on their deficiency and toxicity effects.

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Section: Trace Mineral Status In Camel Bloodsupporting

confidence: 76%

Blood Trace Element Status in Camels: A Review

Abdelrahman

Alhidary

Aljumaah

et al. 2022

Animals

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“…Vitamin A plays essential role in epithelization of many organs and immunomodulation against infection. Additionally, it has been reported that vitamin A is deficient in feeding regimen of the farm animals therefore, its dietary supplementation is very necessary to the ruminant diet (Duester, 2008;Baraka, 2012;Pourjafar et al, 2014). Vitamin E is also involved in many physiological processes against free radicals and poly unsaturated fatty acids that in turn prevent muscular and cellular injury and oxidative stress (Bennett and Brown, 2003;Baraka, 2012).…”

Section: Introductionmentioning

confidence: 99%

“…Trace elements including copper, zinc and selenium had an important antioxidants function; they also play a role in maintaining normal oxidants/antioxidants and immunomodulation (Hambidge, 2003;Nayyar and Jindal, 2010;Pourjafar et al, 2014). Of interest, vitamins and trace elements is a contributory factor in the process of phagocytosis that categorized into chemotaxis (migration of phagocytes to inflammatory sites), attachment of particles to the cell surface of phagocytes, ingestion (phagocytosis) and intracellular killing by oxygen-dependent (oxidative burst) and oxygen independent mechanisms (Roitt et al, 1996;Bhaskaram, 2002;Mehrzad et al, 2014).…”

Section: Introductionmentioning

confidence: 99%

Serum vitamin A and E, copper, zinc and selenium concentrations and their relationship with health outcomes in dromedary hospitalized camels (<i>Camelus dromedarius</i>)

et al. 2018

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The goals of this study were to measure serum vitamin A (retinol) and E (α-tocopherol) and trace elements concentrations (copper, zinc and selenium) during diseases condition and to determine their association with hematological parameters and immune status of hospitalized camels. A total of 95 dromedary camels [healthy (n=65); hospitalized camels (n=30)] were included in this study. Vitamin A and E concentrations were significantly lower in hospitalized camels than apparently healthy ones (P<0.05). Hospitalized camels had lower concentrations of zinc and selenium compared to healthy camels (P<0.05). Vitamin E, copper, zinc and selenium concentrations were positively correlated with phagocytic activity in hospitalized camels (P<0.05). The likelihood of deficiency of vitamin A and E, zinc and selenium concentrations were significant in female hospitalized camels than males and in young age hospitalized camels < 6 years old compared to old ones (P<0.05). Decreased vitamin A and E and trace elements concentrations were associated with hospitalized camels’ phagocytic activity and index. The prevalence of low vitamin A and E, zinc and selenium concentrations were frequent in female hospitalized camels and hospitalized camels of age < 6 years old suggesting severe oxidative stress.

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“…Damage to the skeletal or heart musculature causes a significant rise in serum LDH levels since the majority of the vessels in the body can be thought of as a sufficient reservoir of enzymes liable to be released and identified during pathological situations. As a result, any damage to the vasculature could trigger enzyme leakage, making it a valuable tool in the early detection of pathological conditions (Pourjafar et al., 2013).…”

Section: Discussionmentioning

confidence: 99%

Un‐fractionated heparin counteracts the systemic inflammatory responses and multiple organ damages caused by endotoxaemia in sheep

Ashareyoun

Chalmeh

Pourjafar

2022

Veterinary Medicine & Sci

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Background: Endotoxaemia is believed to be a major cause of mortality and there are several therapeutic regimens for the treatment of this situation.Objectives: The present experimental study was conducted to evaluate acute phase response, cardiovascular and hepatorenal damages following the treatment of Ovine experimental endotoxaemia model employing unfractionated heparin (UFH). Materials and Methods:Twenty clinically healthy 1-year-old fat-tailed ewes were randomly divided into four equal groups, comprising UFH 200, UFH 400, Ctrl+ and Ctrl-. Lipopolysaccharide (LPS) from Escherichia coli serotype O55:B5 at 0.4 μg/kg was administered intravenously to the ewes. UFH (at 200 and 400 IU/kg) was administrated to the UFH 200 and UFH 400 groups, respectively. All the ewes were evaluated clinically before and 1.5, 3, 4.5, 6 and 24 hours after LPS injection. Blood samplings were also performed at those hours. We measured serum concentrations of haptoglobin, interferon-gamma, total antioxidant status, malondialdehyde, cardiac lactate dehydrogenase, cardiac troponin-I, total bilirubin, alanine transaminase and creatinine. Serum concentrations of acute phase response, cardiovascular, hepatic and renal biomarkers and clinical parameters increased significantly following the induction of endotoxaemia in the groups receiving LPS. Results:The significantly lowest concentrations of these parameters at hours 4.5 and 6 among the treatment groups belonged to the UFH 400 sheep.Conclusions: UFH could act as an anti-inflammatory mediator by decreasing inflammatory cytokines and acute phase proteins, modulating oxidative stress biomarkers and reducing multiple organ dysfunction following endotoxaemia in a dose-dependent manner. Furthermore, the anti-inflammatory effects of UFH at 400 IU/kg were significantly higher than another dose. This research examined the effect of two doses of UFH and higher doses may have more anti-inflammatory effects that require further studies.

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Correlations between Serum Trace Elements (Selenium, Copper and Zinc) and Antioxidant Vitamins (Vitamin A, E and C) in Clinically Healthy Dromedary Camels

Cited by 4 publications

References 16 publications

Blood Trace Element Status in Camels: A Review

Blood Trace Element Status in Camels: A Review

Serum vitamin A and E, copper, zinc and selenium concentrations and their relationship with health outcomes in dromedary hospitalized camels (<i>Camelus dromedarius</i>)

Un‐fractionated heparin counteracts the systemic inflammatory responses and multiple organ damages caused by endotoxaemia in sheep

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