Correlations of Different Structural and Functional Characteristics of Arterial Wall With Traditional Cardiovascular Risk Factors in Healthy People of Different Age. Part 2

Стражеско, И. Д.; Ткачева, О. Н.; Акашева, Д. У.; Dudinskaya, Е. N.; Agaltsov, M. V.; Kruglikova, Anna; Браилова, Н. В.; Pykhtina, V. S.; Plokhova, E V; Sharashkina, N. V.; Isaykina, O. Yu.; Выгодин, В А; Boytsov, S. А.

doi:10.20996/1819-6446-2016-12-3-244-252

Cited by 7 publications

(4 citation statements)

References 9 publications

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“…These results show that it is no longer possible to limit the use of classical RF [7,8], as was done until recently when conducting youth screening. Predictive diagnostic advantages of vascular stiffness in comparison with other RF are due to its nature as a "tissue" biomarker in comparison with "circulating" biomarkers such as lipids, C-reactive protein, homocysteine, etc., the level of which constantly fluctuates in the human body [9]. It is believed that arterial stiffness integrates the long-term effect of all present RF [2].…”

Section: Resultsmentioning

confidence: 99%

Vasera-screening of premature vascular aging and its correction in young persons: University Health Center experience

et al. 2020

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Angiological screening was performed to determine the cardio-ankle vascular index (CAVI) in 224 young people to determine their vascular aging phenotype. All subjects were divided into CAVI-tercile groups. According to the experts views the upper tercile of this distribution corresponds to early vascular aging or EVA syndrome. Lower tercile corresponds to favorable one and average tercile – to normal vascular aging. In these CAVI-tercile groups, the representation of individuals with signs of arterial hypertension/prehypertension (AH/PH) and overweight was evaluated. It turned out that among boys and girls with risk factors (RF), carriers of various vascular phenotypes are noted, from favorable one to early vascular aging. Such data indicate the need to form youth risk groups, taking into account the presence of not only classical RF, but also the assessment of vascular stiffness. The obtained data is useful to take into account in the process of youth medical examination in order to further develop more individualized preventive intervention programs for each young person.

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Section: Resultsmentioning

confidence: 99%

Vasera-screening of premature vascular aging and its correction in young persons: University Health Center experience

et al. 2020

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“…Так, Стражеско И. Д. и др. [18] казали наличие прямой умеренной взаимосвязи в общей группе (r=0,24; р<0,001), при этом у женщин она оказалась существенно выше (r=0,47; р<0,001), чем у мужчин (r=0,24; р<0,001). Takaki A, et al [19] также выявили тесную прямую взаимосвязь между ИМТ и CAVI у лиц среднего возраста, страдающих ишемической болезнью сердца.…”

Section: Discussionunclassified

Phenotypes of early and favorable vascular aging in young people depending on the risk factors and presence of connective tissue dysplasia

Евсевьева¹,

Ерёмин

Rostovtseva³

et al. 2020

Cardiovasc Ther Prev

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Aim. To study the main risk factors and signs of connective tissue dysplasia (CTD) in young people according to quartile analysis of cardioankle vascular index (CAVI).Material and methods. The study involved 243 young people (men, 81; women, 162) aged 18-25 years. All subjects were divided into quartile groups depending on CAVI on both sides, or CAVI-R and CAVI-L, determined using the VaSera-1500 system (Fucuda Denshia,Japan). According to the latest guidelines, the 4th quartile of this distribution among persons of the same sex and age corresponds to early vascular aging (EVA) syndrome. The 1st quartile corresponds to favorable vascular aging. We analyzed the main RFs and CTD signs in each of the 4 CAVI quartiles. Data processing was carried out using the Statistica 10.0 software package (StatSoft Inc,USA).Results. The minimum and maximum CAVI in the sample were 3,2 and 7,9. The overwhelming majority of studied risk factors in both sexes were not associated with the stiffness. Only body mass and body mass index increasedwith a decrease in vascular stiffness and vice versa. The average number of external stigmas of dysembryogenesis in young people increased from the 1st to the 4th CAVI quartile, with significant differences in the extreme groups. Such CTD signs as a carpal tunnel syndrome and thumb sign also significantly differed between the 1st and 4th quartiles.Conclusion. The presented results can be used for prevention among young people to form more individualized programs taking into account a comprehensive assessment of vascular aging phenotype and the level of external stigmatization of each young person.

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“…Такие биологические факторы риска (ФР), как избыточная масса тела и артериальная гипертензия (АГ), нередко ассоциированы с поведенческими ФР -нерациональным питанием, курением, гиподинамией и др. [4][5][6]. Многие поведенческие стереотипы, которые затем выступают в роли ФР, приобретают устойчивый характер именно в молодые годы [7,8].…”

Section: материал и методыunclassified

“…Проведенный нами анализ встречаемости ФР у представителей пяти студенческих покурсовых когорт за 6 лет их обучения в медицинском ВУЗе показал значимые тенденции в динамике различных показателей состояния здоровья учащейся молодежи (рис. [1][2][3][4][5][6].…”

Section: результатыunclassified

Prospective analysis of the major risk factors and vascular status in students during the period of education at a medical university

Evsevyeva¹,

Eremin

Sergeeva³

et al. 2023

Russ J Cardiol

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Aim. To study the changes of the major risk factors (RFs) and vascular status in students over six years of their education at a medical university.Material and methods. A total of 667 students aged 17,8±1,2 years were examined in the 1st year and 6th year (162 men, 505 women). Students who entered in the same year were combined into one cohort, while in total 5 cohorts were recruited. The screening examination was carried out as part of the annual intra-university events "Freshman Week", "Graduate Week" by staff of the University Health Center and included the collection of complaints and history, height, body weight, the measurement of peripheral and central blood pressure, as well as the assessment vascular stiffness and metabolic status. Statistical analysis of the material was carried out using SPSS Statistics 23.0.Results. Analysis of RFs in medical students over 6 years showed a significant increase of the prevalence of hypertension/prehypertension, resting tachycardia, obesity/overweight, malnutrition and physical inactivity. An assessment of central and peripheral hemodynamics, as well as vascular stiffness of students, revealed an increase in the level of aortic systolic pressure, combined with an increase in peripheral systolic blood pressure and pulse. At the same time, there was no significant increase in some parameters of vascular stiffness, against the background of a 2-fold increase in the prevalence of overweight. Analysis of the metabolic status reveals a significant change in total cholesterol and triglycerides but no alterations in capillary blood glucose.Conclusion. The data obtained indicate an increase in the prevalence of not only behavioral, but also biological RFs among medical students, as well as the development of preclinical vascular remodeling in them during a six-year education, which can later lead to early cardiovascular diseases. Therefore, widespread screening system of risk factors among students should be developed.

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Correlations of Different Structural and Functional Characteristics of Arterial Wall With Traditional Cardiovascular Risk Factors in Healthy People of Different Age. Part 2

Cited by 7 publications

References 9 publications

Vasera-screening of premature vascular aging and its correction in young persons: University Health Center experience

Vasera-screening of premature vascular aging and its correction in young persons: University Health Center experience

Phenotypes of early and favorable vascular aging in young people depending on the risk factors and presence of connective tissue dysplasia

Prospective analysis of the major risk factors and vascular status in students during the period of education at a medical university

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