Corrigendum to “Protecting group-free syntheses of natural products and biologically active compounds” [Tetrahedron 70 (2014) 8183–8218]

Modular Terpenoid Construction via Catalytic Enantioselective Formation of All-Carbon Quaternary Centers: Total Synthesis of Oridamycin A, Triptoquinones B and C, and Isoiresin

“…Optimal results were obtained using TiCl 4 , which gave the product of Friedel-Crafts cyclization in 81% yield as a 3:1 mixture of regioisomers favoring oridamycin A. The present route to oridamycin A, which is protecting group-free, 20 is the most concise total synthesis and the first asymmetric total synthesis of this natural product.…”

Double Catalytic Kinetic Resolution (DoCKR) of Acyclic anti‐1,3‐Diols: The Additive Horeau Amplification

“…[18] This hiddensymmetry strategy [19] represents the shortest synthesis of this target reported to date. [20] Additionally, no protecting group was required for this synthesis, [21] which involved a unique organocatalytic enantioselective step. [22] In conclusion, we described a highly enantioselective synthetic separation of acyclic anti-1,3-diols, which are ubiquitous structural motifs in nature.…”

Total Synthesis of Swinholide A: An Exposition in Hydrogen-Mediated C–C Bond Formation

“…17c,18 Additionally, by virtue of their highly chemo- and stereoselective nature, enantioselective C-C coupling can be achieved in the absence of protecting groups. 19 Collectively, these attributes contribute to a step-change in efficiency. 17b,c Here, using multiple hydrogen-mediated C-C couplings, we report a 15-step (LLS) total synthesis of swinholide A – a route roughly half the length of the two preexisting total syntheses.…”