2005
DOI: 10.1038/sj.eye.6701895
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Corticosteroid-induced glaucoma: a review of the literature

Abstract: The intraocular pressure rise that can complicate the use of topical or systemic corticosteroid has been recognised for 50 years. More recently, following isolation of the myocilin gene (previously known as the trabecular meshwork inducible glucocorticoid response or TIGR gene), there has been renewed interest in this steroid-responsive phenomenon. Furthermore, the currently fashionable use of injectable intraocular steroids in the management of clinically significant subretinal fluid and macular oedema has re… Show more

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Cited by 382 publications
(252 citation statements)
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“…The incidence of steroid-induced glaucoma appears to be related to dose and duration of application of the medication [31].…”
Section: Discussionmentioning
confidence: 99%
“…The incidence of steroid-induced glaucoma appears to be related to dose and duration of application of the medication [31].…”
Section: Discussionmentioning
confidence: 99%
“…3 Adverse effects of facial steroids on the eye have been reported. 4 Risk factors 5 for developing IOP rise include: pre-existing history or family history of POAG, type 1 diabetes, connective tissue disorder such as rheumatoid arthritis, or high myopia. The elevation in IOP typically occurs within a few weeks of starting steroids and normalises a few weeks after cessation, although IOP may sometimes remain elevated, depending on potency and routes of steroid administration.…”
Section: Discussionmentioning
confidence: 99%
“…In our case, we believe that the blunt ocular trauma sustained was insufficient to cause angle recession but culminated in a greater peripheral increase in anterior chamber depth, iridial concavity, and ultimately the irido-zonular contact necessary for pigment dispersion. [23][24] In our patient, IOP elevation occurred 1 month following initial presentation and steroid use. Steroid-induced glaucoma typically occurs within weeks of initiation of topical steroid therapy, with pressures as high as 60 mm Hg reported following prolonged use.…”
Section: Discussionmentioning
confidence: 99%
“…Steroid-induced glaucoma typically occurs within weeks of initiation of topical steroid therapy, with pressures as high as 60 mm Hg reported following prolonged use. [23][24] …”
Section: Discussionmentioning
confidence: 99%