Corynebacterium species and coryneforms: An update on taxonomy and diseases attributed to these taxa

Bernard, Kathryn

doi:10.1016/j.clinmicnews.2005.01.002

Cited by 19 publications

(18 citation statements)

References 110 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Corynebacterium spp. are difficult to identify at the species level since these microorganisms share phenotypic similarities with other bacteria and require numerous biochemical tests in order to be properly identified by MC (Bernard 2005). This genus has been increasingly isolated in cases of subclinical mastitis and its identification is challenging, which may lead to incorrect genus classification by MC.…”

Section: Discussionmentioning

confidence: 99%

Rapid identification of bovine mastitis pathogens by MALDI-TOF Mass Spectrometry

et al. 2018

View full text Add to dashboard Cite

Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) has been shown to be an alternative method for identification of bacteria via their protein profile spectra, being able to identify bacteria at the genus, species and even at subspecies level. With the aim of large-scale identification of pathogens causing mastitis by this platform, a total of 305 isolates of bacteria identified from cows with subclinical mastitis were analyzed by conventional microbiological culture (MC) as well as by MALDI-TOF MS coupled with Biotyper data processing. Approximately 89% of the identifications performed by MALDI-TOF MS were consistent with results obtained by MC. From the remaining isolates (11%), 6.3% of isolates were classified as misidentified (discordance for both genus and species level), and 4.7% showed identification agreement at the genus level but not at the species level, being classified as unidentified at species level. The disagreement results were mostly associated with identification of Streptococcus and Enterococcus species probably due to the narrow phenotypic similarity between these two genera. These disagreement results suggest that biochemical assays might be prone to identification errors and, MALDI-TOF MS therefore may be an alternative to overcome incorrect species-specific identification. Standard microbiological methods for bovine mastitis diagnosis are time consuming, laborious and prone to errors for some bacteria genera. In our study, we showed that MALDI-TOF MS coupled with Biotyper may be an alternative method for large-scale identification of bacteria isolated from milk samples compared to classical microbiological routine protocols.

show abstract

Section: Discussionmentioning

confidence: 99%

Rapid identification of bovine mastitis pathogens by MALDI-TOF Mass Spectrometry

et al. 2018

View full text Add to dashboard Cite

show abstract

“…C. pseudodiphtheriticum on the other hand can cause pneumonia (occasionally with pseudomembranous formation), keratitis or conjunctivitis. 4 …”

Section: Clinical Significance Of C Urealyticummentioning

confidence: 99%

“…Colonies are characteristically pinpoint, whitish, opaque, smooth, convex, circular, and non-hemolytic. 4 …”

Section: Introductionmentioning

confidence: 99%

Corynebacterium urealyticum: a comprehensive review of an understated organism

Salem¹,

Salem²,

Saber³

et al. 2015

IDR

View full text Add to dashboard Cite

Corynebacterium urealyticum is a Gram positive, slow-growing, lipophilic, multi-drug resistant, urease positive micro-organism with diphtheroid morphology. It has been reported as an opportunistic nosocomial pathogen and as the cause of a variety of diseases including but not limited to cystitis, pyelonephritis, and bacteremia among others. This review serves to describe C. urealyticum with respect to its history, identification, laboratory investigation, relationship to disease and treatment in order to allow increased familiarity with this organism in clinical disease.

show abstract

“…Generally, identification of these taxa is initiated by describing Gram stain observations, details of the colony at 24 h (or later for slower growing species), and catalase and oxidase reactions and establishing whether the isolate is lipophilic (4,19,20). Lipophilic Corynebacterium species grow poorly in broth or as tiny pinpoint colonies in 24 h on standard plate agar but grow more luxuriantly if the agar or broth is supplemented with an exogenous lipid such as sterile Tween 80.…”

mentioning

confidence: 99%

The Genus Corynebacterium and Other Medically Relevant Coryneform-Like Bacteria

2012

Self Cite

View full text Add to dashboard Cite

Catalase-positive Gram-positive bacilli, commonly called “diphtheroids” or “coryneform” bacteria were historically nearly always dismissed as contaminants when recovered from patients, but increasingly have been implicated as the cause of significant infections. These taxa have been underreported, and the taxa were taxonomically confusing. The mechanisms of pathogenesis, especially for newly described taxa, were rarely studied. Antibiotic susceptibility data were relatively scant. In this minireview, clinical relevance, phenotypic and genetic identification methods, matrix-assisted laser desorption ionization–time of flight (MALDI-TOF) evaluations, and antimicrobial susceptibility testing involving species in the genus Corynebacterium and other medically relevant Gram-positive rods, collectively called coryneforms, are described.

show abstract

Corynebacterium species and coryneforms: An update on taxonomy and diseases attributed to these taxa

Cited by 19 publications

References 110 publications

Rapid identification of bovine mastitis pathogens by MALDI-TOF Mass Spectrometry

Rapid identification of bovine mastitis pathogens by MALDI-TOF Mass Spectrometry

Corynebacterium urealyticum: a comprehensive review of an understated organism

The Genus Corynebacterium and Other Medically Relevant Coryneform-Like Bacteria

Contact Info

Product

Resources

About