Coseasonal intracutaneous treatment of hay fever

Allergy in the Aged

“…8 While hypersensitivity to certain substances may disappear, sensitivity to others or a new form of allergy may develop. For example, most commonly bronchial asthma may replace allergic rhinitis, with the hypersensitivity remaining hut with one shock organ being replaced by another.…”

“…8 Involvement of a new shock tissue may make a patient suddenly aware of his allergy. Tauh 4 has emphasized that either seasonal or perennial rhinitis, previously masked as "colds," or prior urticaria usually can he elicited in the history of a patient in whom asthma develops in later life.…”

“…In the young, asthma is rarely fatal despite the high morbidity hut, when asthma begins later in life, it becomes progressively more severe. 8 The asthma which has its onset after age 40 seems to he an entirely different disease from that seen in young atopic individuals. For example, Sherman 5 stated that in his experience 90 per cent of the cases of asthma seen in persons between five and 40 years old are due to inhalant sensitivity, while infectious asthma accounts for 90 per cent of the cases in patients more than 40 at time of onset.…”

Allergen-Based Diagnostic: Novel and Old Methodologies with New Approaches

“…dardized procedure was suggested by Schloss [6] who described a correlation of time with clinical signs, reporting 5-15 min of erythematous reaction after abrasion of the skin in a child with rhinitis, asthma, and eczema. Since then, several techniques to evaluate allergenic sensitization have been described, e.g., intracutaneous test, [7] conjunctival test, [8] intracutaneous test by serial dilutions [9]. Nowadays the best technique to evaluate with safety allergenic sensitization is the SPT.…”

Technique of Serial Dilution Antigen Titration

“…No other solution should ever be used for making test dilutions to be used intracutaneously. (2) To prepare treatment di¬ lutions which will be used in less than six weeks.…”