“…On the other hand, plant-based extracts or differential herbal formulations have been also exhaustively studied in several in vitro models, with different pharmacological actions on several mediators of skin elasticity, according to the following classification: - Elastase inhibitory activity was determined after the use of the plant extracts prepared with Eugenia dysenterica [ 26 ], Gastrodia elata [ 27 ], Litchi sinensis [ 28 ], Magnolia officinalis [ 29 ], Malaxis acuminata [ 30 ], Manilkara zapota [ 14 ], Nephelium lappaceum [ 28 ], Phyllanthus emblica [ 14 ], Sclerocarya birrea [ 31 ], Sylibum marianum [ 14 ], Spatholobus suberectus [ 32 ], Tamarindus indica [ 28 ], and a polyherbal formulation containing Nyctanthes arbor-tristis leaf, unripe and ripe Aegle marmelos fruit pulp, and the terminal meristem of Musa paradisiaca extracts [ 33 ];
- An increase in elastin synthesis or gene expression was observed after treatments with plant extracts of Piper cambodianum [ 34 ] and Bidens pilosa [ 35 ];
- An increase in pro-collagen expression or synthesis was observed after treatments with plant extracts prepared from Alchemilla mollis [ 36 ], Azadirachta indica [ 37 ], Camellia sinensis [ 38 ], Citrus junus [ 39 ], Trapa japonica [ 40 ], and a mixture of plant extracts of Kochia scoparia and Rosa multiflora [ 41 ];
- An increase in collagen synthesis or expression was observed after treatments with plant extracts of Andrographis paniculata [ 42 ], Cassia fistula [ 43 ], Camelia sinensis [ 44 ], Passiflora tarminiana [ 45 ], Physalis peruviana [
…”