In this issue of the journal, Ntani and colleagues 1 from Ghana have published a retrospective observational study looking at the contribution of 24-hours ambulatory blood pressure monitoring (ABPM) to the management of hypertension in patients referred to an outpatient cardiology clinic.The medical records of 97 consecutive patients who had ABPM were reviewed for hypertension diagnosis and changes in management for 6 months post-ABPM. Individuals under 18 years of age were excluded, as were those with a diagnosed secondary cause of hypertension or a cardiovascular event in the prior 6 months.At the first visit, clinical and medication details were recorded, clinic blood pressure (CBP) was recorded by standard techniques, and a 24-hours ABPM undertaken. Based on these initial data, patients were categorized as controlled hypertension (CHT -CBP ≤ 140/90 and average daytime ambulatory BP ≤ 135/85), true uncontrolled hypertension (TUCH -CBP ≥ 140/90 and average daytime ambulatory BP ≥ 135/85), white coat uncontrolled hypertension (WUCH -CBP ≥ 140/90 and average daytime ambulatory BP ≤ 135/85), or masked uncontrolled hypertension (MUCH -CBP ≤ 140/90 and average daytime ambulatory BP ≥ 135/85).Mean age of the 97 patients studied was 55, of whom 52 were female. Average body mass index was 30 kg/m 2 . A total of 85 patients had previously diagnosed hypertension and were on prior antihypertensive therapy, 30% had dyslipidemia and 52.6% were recorded as having pre-existing hypertensive heart disease. Blood pressure medication use at baseline was a mean of 2.0 antihypertensive drugs. Mean CBP at the first visit was 139.7/80.6, and mean average daytime ambulatory BP was 131.3/85.3.A total of 47 (54%) had uncontrolled CBP at baseline vs 44 (50.6%) and uncontrolled average daytime ambulatory BP at baseline, but there was poor correlation between these two groups. Of the 87 patients already on antihypertensive medication, the diagnosis after 24-hours ABPM was CHT 26 (30%), MUCH 14 (16%), WUCH 17 (19.5%), and TUCH 30 (34.5%). Twenty-four-hours ABPM changed CBP-based diagnosis in 31 of these 87 patients (35.6%). (The authors do not provide the post-ABPM diagnosis for the 10 patients not previously on blood pressure medication). At the post-ABPM visit, 45/87 (51.7%) of the patients had their treatment modified, which included 7/87 (8%) discontinuing all medication, and 33 new antihypertensive medications were prescribed.Among the 64 patients in whom CBP records were available for 6 months prior to ABPM and 6 months post-ABPM, there was a significant reduction in mean systolic blood pressure (SBP), −6.2 mm Hg. In the 44 with uncontrolled average daytime ambulatory BP at baseline, the mean SBP reduction was −8.8 mm Hg, and among those with controlled average daytime ambulatory BP at baseline, mean SBP at 6 months post-ABPM was unchanged.As the authors comment, a single ABPM had substantial impact on hypertension diagnosis and management when added to standard CBP, and they provide evidence of significantly improved CBP at 6 mont...