Cost-Effectiveness of Combination Therapy Versus Antidepressant Therapy for Management of Depression in Japan

Abstract

The combined therapy appeared to be cost-effective from the health-care system perspective and the dominant strategy from the social perspective.

Cost-Utility Analyses of Cognitive-Behavioural Therapy of Depression: A Systematic Review

“…All studies considered intervention costs, while 5 studies reported outpatient costs additionally [20,21,22,24,25]. Four studies included inpatient costs and medication [21,22,24,25]. Simon et al [21] and Morrell et al [25] - employing the perspective of the British National Health Services - considered costs for community health services.…”

“…Costs were assessed from a third-party payer perspective mainly. All studies considered intervention costs, while 5 studies reported outpatient costs additionally [20,21,22,24,25]. Four studies included inpatient costs and medication [21,22,24,25].…”

“…Simon et al [21] and Morrell et al [25] - employing the perspective of the British National Health Services - considered costs for community health services. Indirect costs valued by the human capital approach were only considered by Sado et al [22]. …”

“…Combination of CBT and medication was cost-effective in comparison to medication alone [21,22]. Combination therapy was even dominant if the societal perspective was employed in the analyses [22].…”

“…Four studies were modelling studies taking the whole population of a country into account [20,21,22,23]. The remaining 2 studies were randomized controlled trials (RCTs) focussing on specific adult populations, i.e.…”