Cost-effectiveness of Magnetic Resonance (MR) Imaging and MR-guided Targeted Biopsy Versus Systematic Transrectal Ultrasound–Guided Biopsy in Diagnosing Prostate Cancer: A Modelling Study from a Health Care Perspective

Rooij, Maarten de; Crienen, Simone; Witjes, J. Alfred; Barentsz, Jelle O.; Rovers, Maroeska M.; Grutters, Janneke P.C.

doi:10.1016/j.eururo.2013.12.012

Cited by 184 publications

(140 citation statements)

References 35 publications

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“…The high detection rates in the primary setting clearly demonstrate the capability of mpMRI for PCa diagnosis. Furthermore, the results of de Rooij et al [23] suggest that the costs of an image-based technique for men with suspicion of PCa are comparable to those of SB, but with higher quality of life.…”

Section: Discussionmentioning

confidence: 92%

Multiparametric Magnetic Resonance Imaging/Transrectal Ultrasound Fusion Targeted Biopsy of the Prostate: Preliminary Results of a Prospective Single-Centre Study

Junker

Schäfer²,

Heidegger³

et al. 2015

Urol Int

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Purpose: To evaluate multiparametric magnetic resonance imaging/transrectal ultrasound (mpMRI/TRUS) fusion targeted biopsy (TB) of the prostate for prostate cancer (PCa) diagnosis. Patients and Methods: From April 2013 to January 2014, 53 men were included in this prospective single-centre study. The degree of PCa suspicion from mpMRI findings was classified according to the PI-RADS scoring system. Of these, 50 patients underwent both an mpMRI/TRUS fusion TB and a 10-core systematic biopsy (SB) of the prostate and were eligible for analysis. Results: 225 targeted and 500 systematic cores were included in this study. PCa was histologically confirmed in 52.0% of patients (26/50), whereas TB revealed PCa in 46.0% (23/50) and SB in 36.0% (18/50). TB identified PCa in 16.0% of all patients (8/50) that were missed by SB. All told, the targeted core was 2.8 times more likely to be PCa-positive than the systematic core (29.3 vs. 10.4%). Conclusions: mpMRI/TRUS fusion TB of the prostate is safe, practicable and may improve PCa diagnosis using fewer biopsy cores compared to SB.

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Section: Discussionmentioning

confidence: 92%

Multiparametric Magnetic Resonance Imaging/Transrectal Ultrasound Fusion Targeted Biopsy of the Prostate: Preliminary Results of a Prospective Single-Centre Study

Junker

Schäfer²,

Heidegger³

et al. 2015

Urol Int

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show abstract

“…Due to the decreased detection of low-risk prostate cancer when compared to standard biopsy, a targeted biopsy approach may have further beneficial economic and psychological implications. De Rooij et al demonstrated improved cost-effectiveness and quality of life for men with clinical suspicion of prostate cancer using MP-MRI followed by MR-guided biopsy than using conventional systematic biopsy for diagnosis [66]. While there is currently a surge of interest in MRI-targeted prostate biopsy, further studies including large prospective multi-center trials are still awaited prior to a large-scale change to the present status of systematic biopsy as the standard of care.…”

Section: Targeted Biopsymentioning

confidence: 94%

Implementation of Multi-parametric Prostate MRI in Clinical Practice

2015

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While initial implementations of prostate MRI suffered from suboptimal performance in tumor detection, technological advances over the past decade have allowed modern multi-parametric prostate MRI (mpMRI) to achieve high diagnostic accuracy for detection, localization, and staging and thereby impact patient management. A particular emerging application of mpMRI is in the pre-biopsy setting to allow for MRI-targeted biopsy, for instance, through real-time MRI/ultrasound fusion, which may help reduce the over-detection of low-risk disease and selectively detect clinically significant cancers, in comparison with use of standard systematic biopsy alone. mpMRI and MRI-targeted biopsy are spreading beyond the large academic centers to increasingly be adopted within small and community practices. Aims of this review article are to summarize the hardware and sequences used for performing mpMRI, explore patient specific technical considerations, delineate approaches for study interpretation and reporting [including the recent American College of Radiology Prostate Imaging Reporting and Data System (PI-RADS) version 2], and describe challenges and implications relating to the widespread clinical implementation of mpMRI.

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“…Regarding the choice of technique, we could deplore the lack of consideration for non-patient-related motivations such as the desire to limit healthcare costs 28 .…”

Section: Discussionmentioning

confidence: 99%

Transrectal ultrasound-guided prostate biopsies vs. magnetic resonance imaging ultrasound fusion targeted biopsies: Who are the best candidates?

Bey¹,

Gaget²,

Descotes³

et al. 2017

CUAJ

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Cost-effectiveness of Magnetic Resonance (MR) Imaging and MR-guided Targeted Biopsy Versus Systematic Transrectal Ultrasound–Guided Biopsy in Diagnosing Prostate Cancer: A Modelling Study from a Health Care Perspective

Cited by 184 publications

References 35 publications

Multiparametric Magnetic Resonance Imaging/Transrectal Ultrasound Fusion Targeted Biopsy of the Prostate: Preliminary Results of a Prospective Single-Centre Study

Multiparametric Magnetic Resonance Imaging/Transrectal Ultrasound Fusion Targeted Biopsy of the Prostate: Preliminary Results of a Prospective Single-Centre Study

Implementation of Multi-parametric Prostate MRI in Clinical Practice

Transrectal ultrasound-guided prostate biopsies vs. magnetic resonance imaging ultrasound fusion targeted biopsies: Who are the best candidates?

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