Cough reflex attenuation and swallowing dysfunction in sub‐acute post‐stroke patients: prevalence, risk factors, and clinical outcome

Abstract

Prevalence of subacute post-stroke OD and swallow safety impairments was much higher than CRT attenuation, and risk factors strongly differed suggesting that the swallow response receives a stronger cortical control than the cough reflex. OD has a greater impact on PSP clinical outcome than impaired cough, the poorest prognosis being for patients with both airway protective dysfunctions.

The impact of lesion location on dysphagia incidence, pattern and complications in acute stroke. Part 2: Oropharyngeal residue, swallow and cough response, and pneumonia

“…Similarly, Vilardell et al . found no association between stroke laterality and impaired efficacy of the cough response to inhalation of citric acid .…”

“…Impaired cough reflex was not related to lesions in one specific hemisphere in our study. Similarly, Vilardell et al found no association between stroke laterality and impaired efficacy of the cough response to inhalation of citric acid [16].…”

Oropharyngeal dysphagia: when swallowing disorders meet respiratory diseases

“…Preserved swallowing and cough functions are thus essential in preventing deep aspirations and consequent chest infections. If both responses fail, silent aspiration (an aspiration without cough) will occur, a dangerous event because of the difficulties in detecting it clinically and its severe consequences [26].…”

Effect of brain lesions on voluntary cough in patients with supratentorial stroke: an observational study

“…Past studies have shown that the majority of patients with left MCA [13] show weak or absent VC and suggested laterality in VC with the left cerebral hemisphere playing a dominant role in the voluntary control of cough. However, other studies failed to associate RC with a specific hemisphere [8,38].…”