2021
DOI: 10.1183/16000617.0104-2021
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Cough symptom severity in patients with refractory or unexplained chronic cough: a systematic survey and conceptual framework

Abstract: BackgroundCough severity represents an important subjective endpoint in assessing the effectiveness of therapies for patients with chronic cough. Although cough-specific quality of life questionnaires exist, a widely available cough severity instrument with established measurement properties remains unavailable.AimsTo identify and summarise the results of studies reporting on the experience of patients with chronic cough and, in the process, develop a conceptual framework to inform development of a patient-rep… Show more

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Cited by 18 publications
(16 citation statements)
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References 85 publications
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“…A conceptual framework of cough severity based on different domains that address symptoms ranging from urge-to-cough to cough frequency, intensity, duration and associated features has been proposed. 12 Until such questionnaires are validated, patient-reported outcome measures, like the LCQ, will likely continue to be used predominantly in clinical practice. The data presented here will assist practitioners in assessing degree of severity of quality-of-life impacts of cough at treatment onset and when assessing treatment response.…”
Section: Discussionmentioning
confidence: 99%
“…A conceptual framework of cough severity based on different domains that address symptoms ranging from urge-to-cough to cough frequency, intensity, duration and associated features has been proposed. 12 Until such questionnaires are validated, patient-reported outcome measures, like the LCQ, will likely continue to be used predominantly in clinical practice. The data presented here will assist practitioners in assessing degree of severity of quality-of-life impacts of cough at treatment onset and when assessing treatment response.…”
Section: Discussionmentioning
confidence: 99%
“…led the focus group discussions over Zoom videoconferencing, each for 60–90 min. A prior systematic survey [ 16 ] informed an initial draft of the interview guide that was subsequently revised based on input from the steering group (G.H.G., I.S.). The facilitator asked open-ended questions, followed by directed questions on themes identified from the systematic survey.…”
Section: Methodsmentioning
confidence: 99%
“…We used directed content analysis, informed by a prior conceptual framework [ 16 ], to identify related themes [ 20 ]. Two researchers (E.K., C.M.)…”
Section: Methodsmentioning
confidence: 99%
See 1 more Smart Citation
“…The McMaster cough severity questionnaire is a newly developed cough symptom severity instrument for RCC patients and provided 43 items addressing the following domains: urge-to-cough sensations (subdomains: frequency and intensity) and cough symptom (subdomains: frequency, control, bout duration, intensity, and associated features/sequelae) ( 186 , 195 ). This currently is a conceptual framework.…”
Section: Assessing Cough As An Outcomementioning
confidence: 99%