Abstract. The increasing energy consumption of large-scale high performance resources raises technical and economical concerns. A reduction of consumed energy in multicore systems is possible to some extent with an optimized usage of computing and memory resources that is tailored to specific HPC applications. The essential step towards more sustainable consumption of energy is its reliable measurements for each component of the system and selection of optimally configured resources for specific applications. This paper briefly surveys the current approaches for measuring and profiling power consumption in large scale systems. Then, a practical case study of a real-time power measurement of multicore computing system is presented on two real HPC applications: maximum clique algorithm and numerical weather prediction model. We assume that the computing resources are allocated in a HPC cloud on a pay-per-use basis. The measurements demonstrate that the minimal energy is consumed when all available cores (up to the scaling limit for a particular application) are used on their maximal frequencies and with threads binded to the cores.Key words: Energy efficiency, high-performance, maximum clique, numerical weather prediction AMS subject classifications. 65Y05, 68U201. Introduction. Nowadays, a large number of hard problems is being solved efficiently on large-scale computing systems such as clusters, grids and clouds. The main building blocks of such systems are highperformance computing (HPC) clusters, since they are furthermore embedded both into grid computing systems as well as cloud computing systems [1]. A great advantage of Graphical Processor Unit (GPU) accelerators over multicore platforms was demonstrated in terms of energy efficiency [2] with an overall energy consumption for an order of magnitude smaller for the GPUs. Inside the clusters, the many-core architectures, such as GPUs [3], as well as even more specialized data-flow computers [4] are getting an increasingly large supporting role but the main processing is still performed by the multi-core main processors because of simple programming model.In this research, we analyze the energy consumption profile of the processors on a two processor multi-core computer, while varying its workload.With the increasing number of components in large-scale computing systems the energy consumption is steeply increasing [5]. In computer systems, energy (measured in Joules) is represented as the electricity resource that can power the hardware components to do computation. On the other hand, power is the amount of energy consumed per unit time (measured in Joules per second or Watts). The ever-increasing energy consumption of large-scale computing systems causes higher operation costs (e.g. electricity bills) and has negative environmental impacts (e.g. carbon dioxide emissions). Therefore, when designing large-scale computing systems, the focus is often shifting from performance improvements to energy efficiency.Energy can be reduced at several levels of the distrib...