Course of Illness and Treatment Updates for Bipolar Disorder in the Perinatal Period

Batt, Melissa M.; Olsavsky, Aviva K.; Dardar, Shaleah; John-Larkin, Celeste St.; Johnson, Rachel L.; Sammel, Mary D.

doi:10.1007/s11920-022-01323-6

Cited by 6 publications

(3 citation statements)

References 70 publications

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“…This is a novelty because other recent synonymous systematic reviews were concerned with the identification of factors associated with relapse, but they focus on specific phases, such as the review by Rusner et al [ 17 ], which focused specifically on the period of pregnancy and birth, and specifically, on adverse medical events in the mother and child. Recent work has been published that focuses on identifying risk factors at different stages of a woman’s life, although these are non-systematic narrative reviews [ 53 ]. Other systematic reviews focus on making important nosological distinctions, such as the difference in the risk of relapse between women with BD and women with a history of postpartum psychosis [ 4 ], or the importance of the phenomenon of hypomania, or high, in the postpartum period in women [ 40 ].…”

Section: Discussionmentioning

confidence: 99%

Postpartum Relapse in Patients with Bipolar Disorder

Conejo-Galindo

Sanz-Giancola

Álvarez-Mon

et al. 2022

JCM

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Pregnancy and postpartum are vital times of greater vulnerability to suffer a decompensation of bipolar disorder (BD). Methods: A systematic literature search was performed on public electronic medical databases, following PRISMA guidelines. Studies were included if they reported postpartum relapse in patients diagnosed with BD according to Diagnosis Statistical Manual (DSM) or International Classification Disease (ICD) criteria. Results: Sixteen articles describing 6064 deliveries of 3977 women were included in the quantitative analyses. The overall risk of postpartum relapse was 36.77%. The methodology of the studies, the diagnostic criteria, the discrimination between BD type I and II, and the origin of the sample were very heterogeneous. Conclusions: the rate of postpartum bipolar relapse is very high, as it is considered to be a critical period. It is especially important to detect decompensation in this period and to evaluate mood-stabilizing treatment, given the high risk of relapse concentrated in a short period.

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Section: Discussionmentioning

confidence: 99%

Postpartum Relapse in Patients with Bipolar Disorder

Conejo-Galindo

Sanz-Giancola

Álvarez-Mon

et al. 2022

JCM

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“…Antipsychotic medications are being more commonly prescribed to women during pregnancy who have bipolar disorder and schizophrenia. Research on the occurrence of congenital malformations, cardiac anomalies, extrapyramidal symptoms, neonatal withdrawal/abstinence syndrome, and the enduring neurodevelopmental consequences resulting from exposure to these medications has been limited (Batt et al, 2022;Clark, 2020).…”

Section: Introductionmentioning

confidence: 99%

The effect of antipsychotic treatment, during the perinatal period, on the neurodevelopment of children: a systematic review and meta-analysis

Andrianopoulou,

Galanis,

Alevizopoulos

2023

Preprint

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Background Managing mental disorders in the perinatal period is a challenge. The most common mental disorders encountered in this period are major depression, bipolar disorder, anxiety and psychotic disorders. Purpose This study aimed to investigate the neurodevelopmental effects in children born to mothers who were on antipsychotic medication, during pregnancy. Methodology: Databases MEDLINE, Embase, Cochrane, PsychInfo, Google Scholar and Scopus searched according to inclusion and exclusion criteria. The studies involved mothers with preconception or relapsed mental illness receiving antipsychotic medication during the perinatal period and their children were screened for any neurodevelopmental disorders. From the initial search of the literature, 277 articles emerged and applying the criteria, according to the methodology, we identified 15 articles. Results Three studies were identified in which children were exposed and developed ADHD with a pooled odds ratio of 2.33 (95% CI = 1.69–3.20, p < 0.001) indicating that children exposed to antipsychotics are more likely to develop ADHD than unexposed children. Regarding socio-emotional and mental development, it was found that the pooled odds ratio was 2.33 (95% CI = 1.68–3.22, p < 0.001) indicating that exposed children are more likely to show delay compared to unexposed children. This relationship was statistically significant. Finally, it was found that children who were exposed and showed a delay in motor development had a pooled odds ratio of 2.93 (95% CI = 1.86–4.61, p < 0.001). Discussion Fetal exposure to antipsychotic medication can cause short-term developmental delays in motor, social-emotional, and adaptive behavior. However, further investigation is needed since the number of studies.

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“…Por otra parte, el embarazo en los TB se ha asociado más frecuentemente con evoluciones obstétricas y neonatales adversas como partos prematuros, cesáreas, hipertensión y diabetes gestacional, hemorragias obstétricas y recién nacidos pequeños o grandes para la edad gestacional (Batt et al, 2022;Clark y Wisner, 2018;Rusner et al, 2016).…”

Section: Introductionunclassified

Tercer Consenso Argentino sobre el manejo de los Trastornos Bipolares. Tercera parte: Manejo de los Trastornos Bipolares en el contexto de situaciones especiales

Cetkovich-Bakmas,

Abadi,

Camino

et al. 2023

Vertex Rev Arg Psiquiatr

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Este documento constituye la tercera y última parte del Tercer Consenso Argentino sobre el Manejo de los Trastornos Bipolares llevada a cabo por la Asociación Argentina de Psiquiatría Biológica (AAPB). Siguiendo con el objetivo propuesto por el comité de expertos, en la actual versión del Consenso sobre el manejo de los trastornos bipolares, esta sección está enfocada al abordaje de los Trastornos Bipolares en situaciones especiales. Esto configura una revisión exhaustiva de la evidencia científica sobre: a) el manejo de los trastornos bipolares en pacientes resistentes al tratamiento, b) el manejo de los trastornos bipolares en la mujer en el período perinatal, c) el manejo del trastorno bipolar en la etapa infantojuvenil y d) el manejo de los trastornos bipolares en los adultos mayores.

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Course of Illness and Treatment Updates for Bipolar Disorder in the Perinatal Period

Cited by 6 publications

References 70 publications

Postpartum Relapse in Patients with Bipolar Disorder

Postpartum Relapse in Patients with Bipolar Disorder

The effect of antipsychotic treatment, during the perinatal period, on the neurodevelopment of children: a systematic review and meta-analysis

Tercer Consenso Argentino sobre el manejo de los Trastornos Bipolares. Tercera parte: Manejo de los Trastornos Bipolares en el contexto de situaciones especiales

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