Covalent photolinker-mediated immobilization of an intermediate dextran layer to polymer-coated surfaces for biosensing applications

Waveguide interrogated optical immunosensor (WIOS) for detection of sulfonamide antibiotics in milk

“…The surface of the chips was functionalized with a polymeric layer, OptoDex ® (Arrayon Biotechnology SA, Neuchâtel, Switzerland), a photopolymerizable dextran layer that allows covalent binding of biomolecules after exposure to UV light (Barie et al, 1998;Caelen et al, 2002). In addition, the OptoDex ® layer prevents non-specific adsorption from molecules in solution.…”

Emerging biomedical sensing technologies and their applications

“…Several immobilization techniques, surface modification methods, and a variety of novel intermediate materials supporting the attachment have been studied extensively [106]. In particular, several polymer-based interfaces have been proposed [107], [108]. One technique is a new very promising polymer nanofiber structure for cell immobilization [109].…”

Photopolymerizable Materials in Biosensorics

“…Typically photo-linking prepared polymers are used (Jae Ho Shin et al, 1998;Jobst et al, 1993;Nakako at al., 1986;Barie et al, 1998;Dobrikov & Shishkin, 1983a, 1983bDontha et al, 1997;Leca et al, 1995;Nakayama & Matsuda, 1992;Nakayama et al, 1995;Navera et al, 1991). Polyvinyl derivatives such as polyvinyl chloride were widely used at the creation of biosensors (Jae Ho Shin et al, 1998).…”

“…Decline in response for 3 months was 12% only. At the development of immune biosensors based on surface acoustic waves to detect a specific protein (urease) as photo-crossing agent served bovine serum albumin (BSA) modified aryldiazirine (Barie et al, 1998). Aryldiazirine absorbs light with a wavelength of 350 nm and forms a highly reactive carbenes, which are preferably interact with the C-H, C-C, C=C, N-H, O-H or S-H groups.…”