Covalently immobilized aminonaphthalimide as fluorescent carrier for the preparation of optical sensors

Abstract

By replacing the hydrogen of the 4-amino group of a 4-amino-1,8-naphthalimide derivative with an N-acryloxyethyl group, the fluorophore has been covalently immobilized on an optical sensor surface by UV photopolymerization. The optical sensor obtained can be used for the determination of picric acid. The linear range and detection limit of the sensor are 9.80x10(-7)-1.96x10(-4) mol L(-1) and 7.1x10(-7) mol L(-1), respectively. Leaching of the fluorophore from the membrane is effectively prevented by covalent immobilization, resulting in a sensor with a relatively long lifetime. The response time of the sensor is short, and the reproducibility and reversibility are good. The sensor has been used for the indirect determination of the chloroquine content of pharmaceutical tablets.

Fiber-Optic Sensor for Iodine Based on a Covalently Immobilized Aminobenzanthrone Schiff Base

“…A homemade poly(tetrafluoroethylene) flow-cell and a bifurcated fiber were used for iodine sensing measurements. 23 The excitation light was carried to the cell through one arm of a bifurcated optical fiber, and the emission light collected through the other. A glass plate (diameter 13 mm) covered with a sensing membrane was fixed on the top of the flow chamber by a mounting screw nut with the membrane in contact with the sample solution.…”

A novel fluorescence sensor based on covalent immobilization of 3-amino-9-ethylcarbazole by using silver nanoparticles as bridges and carriers

“…Immobilization techniques of indicator dyes have significant effects on the performance of the optical sensors in terms of sensitivity and stability. The indicator dyes can be physically [1][2][3][4][5][6][7][8][9][10] and chemically [11][12][13][14][15][16][17][18][19] immobilized onto the support matrixes. Physical techniques are very simple ways to immobilize indicator dyes and can give high yields at low cost, the durability of the sensing layers fabricated thereby is relatively poor since the indicator dyes can be easily leaked out of the matrixes.…”

“…Tan). [16][17][18][19], the obtained sensors showed no dye-leaching, but it was difficult to control the thickness of the sensing films in the preparing process of sensors, and sometimes it was not easy to restore the fluorescence intensity of the sensor to the blank value by simply rinsing after the sensor was used. The reason is that the indicator dyes or dye-analyte complexes are distributed in the total sensing layer rather than on its outmost surface.…”

Optochemical Sensor for an Ornidazole Assay Using 1-Amino-4-allyloxyanthraquinone as a Fluorescent Indicator

“…[13][14][15][16][17][18][19] The covalent immobilization of sensitive molecules has attracted research interest since it prevents the leaching of sensitive components from the organic membrane phase into sample solutions, and results in an enhanced lifetime of the sensors. Therefore, an optochemical sensor based on a covalent immobilization technique was designed in the present work.…”