COVID-19 and Acute Pulmonary Embolism in Postpartum Patient

Abstract

We report a 36-year-old woman in Iran who sought care for left shoulder pain and cough 5 days after a scheduled cesarean section. Acute pulmonary embolism and coronavirus disease were diagnosed. Physicians should be aware of the potential for these concurrent conditions in postpartum women.

Dual catastrophe of COVID-19: Massive pulmonary embolism and stroke in a previously healthy young patient: A case report

“…Our patient had severe fatal COVID-19 pneumonia with multi-organ failure, massive PE, MCA stroke, spleen, and kidney infarcts. This drastic case presentation concurs with linking other published cases linking stroke, large vessel occlusion, and PE with COVID-19 ( 5 , 6 , 10 , 11 ). Another prospective cohort study with autopsy findings of venous thromboembolism in patients with COVID-19 showed that deep venous thrombosis was present in 7 of 12 patients (58%) in whom venous thromboembolism (VTE) was not suspected before death, and PE was the direct cause of death in four patients ( 7 ).…”

“…There is a tsunami of emerging COVID-19 research indicating that COVID-19 is a multi-organ systemic disease that can cause diverse pathologic changes, such as large vessel stroke, venous thromboembolism, micro thrombosis, myocardial injury, neurological sequelae, pulmonary disease, renal and hepatic dysfunction ( [5] , [6] , [7] , [8] , [9] , [10] , [11] , [12] , [13] ).…”

Late acute pulmonary embolism after mild Coronavirus Disease 2019 (COVID-19): a case series

“…Firstly, several studies reported the occurrence of thromboembolic phenomenon in inpatient settings, especially in ICU patients with severe or critical COVID-19 12,13,[24][25][26][27] . Secondly, in a PubMed search for papers concerning thromboembolic events after mild COVID-19 cases, we retrieved only ten articles [14][15][16][17][18][19][20][21][22][23] .…”

“…According to the last WHO report, patients with mild COVID-19 recover within two weeks 28 . A few studies reported cases of mild COVID-19 that complicated with venous thromboembolism events still in the active phase of the disease [14][15][16][17][18][19] . In contrast, in our cases, the pulmonary embolism occurred in the COVID-19 convalescence phase, when the symptoms related to the acute illness had already disappeared.…”

“…Most of the studies reported thromboembolic events in patients with COVID-19 admitted to the hospital. A PubMed search for articles published up to July 31, 2020 using the following search strategy -("Thrombosis" OR "Embolism" OR "Thromboemb*") AND "COVID-19"found ten articles reporting cases of VTE in patients after mild COVID-19 [14][15][16][17][18][19][20][21][22][23] . Here we describe a case series of five patients with mild COVID-19 that, after an apparent clinical improvement, developed acute pulmonary embolism more than fourteen days after the onset of symptoms.…”