COVID-19 dermatological manifestations

Abstract

COVID-19 is an ongoing multisystemic viral infection, which affects both adults and children. The virus has a complicated and not fully understood pathophysiological mechanism of damaging different organs and systems, including the skin. Cutaneous manifestations classification is complicated by the great variety of lesions and histological appearances, neither specific. Herein, a thorough overview of the clinical and pathological peculiarities of skin changes observed in the acute and re-convalescent stages of COVID-19 infection, is highlighted. The pathophysiological mechanisms, suggested to trigger and sustain the dermatological dysfunction, are also considered in the vicinity of authors’ personal experience.