COVID-19 in Children: Clinical Characteristics and Follow-Up Study

Ruan, Pei-Sen; Xu, Hongbo; Wu, Junhua; Song, Qifan; Qiu, Haiyan

doi:10.1007/s42399-020-00502-x

Cited by 3 publications

(3 citation statements)

References 8 publications

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“…A majority of children contracted the disease from adults in their families. Similar family clustering of pediatric cases has been reported earlier [2][3][4][5]. However, children may get the disease from non-family members also and hence children should also be encouraged to follow precautions at a personal and social level.…”

Section: Discussionsupporting

confidence: 71%

Epidemiological and clinical profile of COVID-positive children without comorbidities: Observations from a dedicated COVID hospital in East India

Kumar¹,

Kumari²,

Singh³

et al. 2021

Indian J Child Health

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A lthough all humans are susceptible to severe acute respiratory syndrome coronavirus (SARS-CoV-2) viral infection, it does appear that coronavirus disease (COVID)-19 disease occurs less frequently and less severely in children than in adults. Reports of pediatric cases are increasing nonetheless [1][2][3]. However, we could not find any such study from this region so we planned this study to present the epidemiological and clinical profile of COVID-positive children without any comorbidity. MATERIALS AND METHODSA retrospective observational study was conducted at Central Hospital, Ramgarh, dedicated COVID care hospital in the eastern state of Jharkhand. We reviewed the case files of all patients <18 years of age admitted in our hospital from May 2020 to October 2020. Among them, those who tested positive for SARS-CoV-2 infection by reverse transcriptase polymerase chain reaction (RTPCR) by nasopharyngeal swab without preexisting comorbidities were included in the study. Children with pre-existing conditions such as malignancy, hematological conditions (sickle cell, thalassemia, and hemophilia), congenital heart disease, chronic lung disease, chronic kidney disease, and multiple congenital anomalies were excluded from the study.Information of all enrolled patients were noted in a predesigned pro forma which included details such as age, sex, history of contact, history of travel to endemic area, presenting complaints, clinical examination, investigations, and treatment received. Total duration of disease was taken as the interval between first RTPCR-positive reports to first RTPCR-negative report. Data were entered into MS Excel and statistically analyzed using SPSS

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Section: Discussionsupporting

confidence: 71%

Epidemiological and clinical profile of COVID-positive children without comorbidities: Observations from a dedicated COVID hospital in East India

Kumar¹,

Kumari²,

Singh³

et al. 2021

Indian J Child Health

View full text Add to dashboard Cite

show abstract

“…Much positive changes have happened in child and adolescent health in recent years but children and youth growing up today face new and unprecedented threats to their health [ 14 ]. The COVID-19 pandemic has exacerbated many of these threats, jeopardizing child welfare gains and causing a global economic and health crisis, which will impact children and adolescents in terms of economic disadvantage, health and access to services [ 15 , 16 ].…”

Section: Discussionmentioning

confidence: 99%

Global Burden of Headache Disorders in Children and Adolescents 2007–2017

Leonardi

Grazzi

D’Amico

et al. 2020

IJERPH

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Headache disorders are prevalent and disabling conditions impacting on people of all ages, including children and adolescents with substantial impact on their school activities and leisure time. Our study aims to report specific information on headaches in children and adolescents based on the Global Burden of Disease (GBD) study, that provides estimates for incidence, prevalence, fatal and non-fatal outcomes. We relied on 2007 and 2017 GBD estimates for prevalence and Years Lived with Disability (YLDs) at the global level and in WHO regions. The results show that, migraine and tension-type headache (TTH) together account for 37.5% of all-cause prevalence and for 7% of all-cause YLDs. Over the past decade, prevalence rates showed a mild increase of TTH in all ages and of migraine alone for adolescents. The YLDs increased among females of all ages with some regional differences that might be connected to the unequal availability of effective acute and prophylactic treatments across world regions. GBD data support the need to promote public health policies and strategies including diagnosis, pharmacological and non-pharmacological treatments that are expected to help reduce the disability and burden associated to migraine and TTH among children and adolescents.

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“…These included one case of infection with Aspergillus flavus , one case with Candida glabrata , and three cases with Candida albicans [ 12 ]. Another study reported that patients with COVID-19 showed a higher percentage (8–15%) of secondary infections [ 13 , 14 ]. Koehler et al [ 7 ].…”

Section: Introductionmentioning

confidence: 99%

Antifungal Effect of Nanoparticles against COVID-19 Linked Black Fungus: A Perspective on Biomedical Applications

Gurunathan

Lee

Kim

2022

IJMS

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Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly transmissible and pathogenic coronavirus that has caused a ‘coronavirus disease 2019’ (COVID-19) pandemic in multiple waves, which threatens human health and public safety. During this pandemic, some patients with COVID-19 acquired secondary infections, such as mucormycosis, also known as black fungus disease. Mucormycosis is a serious, acute, and deadly fungal infection caused by Mucorales-related fungal species, and it spreads rapidly. Hence, prompt diagnosis and treatment are necessary to avoid high mortality and morbidity rates. Major risk factors for this disease include uncontrolled diabetes mellitus and immunosuppression that can also facilitate increases in mucormycosis infections. The extensive use of steroids to prevent the worsening of COVID-19 can lead to black fungus infection. Generally, antifungal agents dedicated to medical applications must be biocompatible, non-toxic, easily soluble, efficient, and hypoallergenic. They should also provide long-term protection against fungal growth. COVID-19-related black fungus infection causes a severe increase in fatalities. Therefore, there is a strong need for the development of novel and efficient antimicrobial agents. Recently, nanoparticle-containing products available in the market have been used as antimicrobial agents to prevent bacterial growth, but little is known about their efficacy with respect to preventing fungal growth, especially black fungus. The present review focuses on the effect of various types of metal nanoparticles, specifically those containing silver, zinc oxide, gold, copper, titanium, magnetic, iron, and carbon, on the growth of various types of fungi. We particularly focused on how these nanoparticles can impact the growth of black fungus. We also discussed black fungus co-infection in the context of the global COVID-19 outbreak, and management and guidelines to help control COVID-19-associated black fungus infection. Finally, this review aimed to elucidate the relationship between COVID-19 and mucormycosis.

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COVID-19 in Children: Clinical Characteristics and Follow-Up Study

Cited by 3 publications

References 8 publications

Epidemiological and clinical profile of COVID-positive children without comorbidities: Observations from a dedicated COVID hospital in East India

Epidemiological and clinical profile of COVID-positive children without comorbidities: Observations from a dedicated COVID hospital in East India

Global Burden of Headache Disorders in Children and Adolescents 2007–2017

Antifungal Effect of Nanoparticles against COVID-19 Linked Black Fungus: A Perspective on Biomedical Applications

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