COVID-19 vaccine acceptance rate and its predictors in Ethiopia: A systematic review and meta-analysis

Abstract

Coronavirus disease (COVID-19) is a global pandemic caused by the SARS-CoV-2 virus. COVID-19 vaccine is the best strategy for prevention. However, it remained the main challenge. Therefore, this systematic review and meta-analysis aimed to determine the overall pooled estimate of COVID-19 vaccine acceptance and its predictors in Ethiopia. Consequently, we have searched articles from PubMed, EMBASE, Web of Science, Google Scholar, reference lists of included studies, and Ethiopian universities’ research repository. The weighted inverse variance random effects model was employed. The quality of studies and the overall variation between studies were checked through Joanna Briggs Institute (JBI) quality appraisal criteria and heterogeneity test (I 2 ), respectively. The funnel plot and Egger’s regression test were also conducted. Following that, a total of 14 studies with 6,773 participants were considered in the study and the overall pooled proportion of COVID-19 vaccine acceptance was 51.2% (95% CI: 43.9, 58.5). Having good knowledge (Odds ratio: 2.7; 95% CI: 1.1, 7.1; P.value: 0.00), chronic disease (Odds ratio: 2; 95% CI: 1.3, 3.1), older age (Odds ratio: 1.8; 95% CI: 1.1, 3.0; P.value: 0.02), and secondary education and above (Odds ratio: 3.3; 95% CI: 1.7, 6.7; P.value: 0.00) were significantly associated with the acceptance of COVID-19 vaccine. In conclusion, Having good knowledge, chronic disease, older age, and secondary education and above were significantly associated with COVID-19 vaccine acceptance. Therefore, special attention and a strengthened awareness, education, and training about COVID-19 vaccine benefits had to be given to uneducated segments of the population.

Predictors of Willingness to Accept COVID-19 Vaccine Among Adult Clients Attending Bule Hora University Teaching Hospital,West Guji Southern Ethiopia

“…This nding is in line with the study conducted in Wolaita Sodo town [27], in Gurage Zone [3], systemic review and meta-analysis Ethiopia [42]. The possible reasons could be health education, burden of disease and rst priority was given for individual with chronic disease to be vaccinated rst.…”

“…In this study, clients with good knowledge were 2 times more likely willing to accept COVID-19 vaccine than those with poor knowledge. This is consistent with systematic review and meta-analysis in East Africa [31], in Ethiopia [42], North East Ethiopia[26], southern Ethiopia among adult population [3] and southern Ethiopia on lactating mothers [25].The possible explanation could be those who had awareness of the vaccine might know the bene t of being Vaccinated such as halting the transmission of new COVID-19 infections and preventing the Possibility of further morbidity and mortality caused by infections.…”

Willingness to accept COVID-19 vaccine and its determinants in Ethiopia: A systematic review and meta-analysis

“…Few studies conducted in Ethiopia recently utilized limited number of studies, and missed some variables like attitude of the public towards the vaccine uptake (11)(12)(13)(14). A number of associated factors were identified so far regarding the willingness of people to take COVID-19 vaccines; perceived susceptibility, safety (fear of side effects), willingness to pay for the vaccine, history of contracting COVID-19, knowledge regarding COVID-19, sex, occupation, religion, age and marital status (9,15,16).…”

COVID-19 vaccine acceptance and its association with knowledge and attitude among patients with chronic diseases in Ethiopia

“…However, studies have shown that the acceptance and uptake rate of COVID-19 vaccination among chronic disease populations are relatively lower than the expected standards. 23–37 …”

“…Previous studies with inconsistent findings revealed that populations with chronic diseases had a higher probability of accepting the COVID-19 vaccine in Ethiopia. 23 , 25 , 31 , 38–40 However, there have been no pooled measures for the COVID-19 vaccine acceptance by patients with chronic diseases in Ethiopia. In addition, primary studies have shown that the association of knowledge and attitude toward the COVID-19 vaccine acceptance among patients with chronic diseases had inconsistent findings in Ethiopia.…”