COVID-19 vaccine and pregnancy: A safety weapon against pandemic

Magon, Navneet; Prasad, Shail; Mahato, Chandrashekhar; Sharma, Jai Bhagwan

doi:10.1016/j.tjog.2022.02.005

Cited by 19 publications

(22 citation statements)

References 22 publications

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“…Evolving recommendations and misinformation had led to some understandable hesitancy among pregnant women when COVID-19 vaccines were first authorized. Since the end of our data collection, evidence about the safety and effectiveness of the COVID-19 vaccines in pregnancy has become more available, providing assurance that the benefits of vaccination (especially in settings with high rates of COVID-19 infection) is in favour of vaccination for pregnant women [ 32 , 33 ]. Those responsible for maternal and neonatal health in many countries have now approved the COVID-19 immunization in pregnancy [ 34 ].…”

Section: Discussionmentioning

confidence: 99%

Pregnancy during COVID-19: social contact patterns and vaccine coverage of pregnant women from CoMix in 19 European countries

Wong

Gimma²,

Paixão³

et al. 2022

BMC Pregnancy Childbirth

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Background Evidence and advice for pregnant women evolved during the COVID-19 pandemic. We studied social contact behaviour and vaccine uptake in pregnant women between March 2020 and September 2021 in 19 European countries. Methods In each country, repeated online survey data were collected from a panel of nationally-representative participants. We calculated the adjusted mean number of contacts reported with an individual-level generalized additive mixed model, modelled using the negative binomial distribution and a log link function. Mean proportion of people in isolation or quarantine, and vaccination coverage by pregnancy status and gender were calculated using a clustered bootstrap. Findings We recorded 4,129 observations from 1,041 pregnant women, and 115,359 observations from 29,860 non-pregnant individuals aged 18–49. Pregnant women made slightly fewer contacts (3.6, 95%CI = 3.5–3.7) than non-pregnant women (4.0, 95%CI = 3.9–4.0), driven by fewer work contacts but marginally more contacts in non-essential social settings. Approximately 15–20% pregnant and 5% of non-pregnant individuals reported to be in isolation and quarantine for large parts of the study period. COVID-19 vaccine coverage was higher in pregnant women than in non-pregnant women between January and April 2021. Since May 2021, vaccination in non-pregnant women began to increase and surpassed that in pregnant women. Interpretation Limited social contact to avoid pathogen exposure during the COVID-19 pandemic has been a challenge to many, especially women going through pregnancy. More recognition of maternal social support desire is needed in the ongoing pandemic. As COVID-19 vaccination continues to remain an important pillar of outbreak response, strategies to promote correct information can provide reassurance and facilitate informed pregnancy vaccine decisions in this vulnerable group.

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Section: Discussionmentioning

confidence: 99%

Pregnancy during COVID-19: social contact patterns and vaccine coverage of pregnant women from CoMix in 19 European countries

Wong

Gimma²,

Paixão³

et al. 2022

BMC Pregnancy Childbirth

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“…While COVID-19 infection escalates the risk of severe illness and death in pregnant women, pregnant women were not integrated in the primary vaccine trials. 32 Consequently, safety information is scarce. Countries have different recommendations, yet they have approved the COVID-19 immunization in pregnancy after a risk-benefit analysis.…”

Section: Introductionmentioning

confidence: 99%

“…Countries have different recommendations, yet they have approved the COVID-19 immunization in pregnancy after a risk-benefit analysis. 32 However, the Joint Committee on Vaccination and Immunization (JCVI) of the United Kingdom lately endorsed an mRNA vaccination for pregnant women. Immunization is also commended by the CDC, ACOG, ARFM, and WHO.…”

Section: Introductionmentioning

confidence: 99%

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COVID-19 vaccination in pregnancy: A review of maternal and infant benefits

Lamptey

Senkyire

Banoya

et al. 2022

gocm

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Pregnant women with COVID-19 are more likely to be admitted to the intensive care unit and their babies born prematurely. Clinical trials excluded pregnant women from the vaccine and safety data were limited. However, an increasing number of studies have demonstrated the safety and immunogenicity of the COVID-19 vaccines for pregnant women and their babies including evidence of maternal transfer of antibodies. In addition to these benefits, the vaccines are proved to be effective for both the pregnant women and infants. The current evidence supports the safety, immunogenicity of the COVID-19 vaccine and its effectiveness in reducing the theoretical risk of the infection among pregnant women and their infants. This review summarizes the recent data on the beneficial effects of COVID-19 immunization on both the pregnant mother and infant.

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“…Taken together, some authors claimed that the COVID-19 vaccine is a safety weapon against the COVID-19 pandemic for pregnant women, 14 as well as our previous review 2 and current comment favoring the COVID-19 vaccination to the pregnant women or other populations vulnerable to infectious disease; 2,15 however, there is no doubt that we are eagerly looking forward to learning more work attempting to achieve equity in the availability, acceptance, and administration of life-saving interventions, such as the COVID-19 vaccines.…”

mentioning

confidence: 99%