COVID-19 vaccine is correlated with favourable epidemiological indicators in the Auvergne-Rhône-Alpes region (France): An ecological study

Romain-Scelle, Nicolas; Elias, Christelle; Vanhems, Philippe

doi:10.1016/j.vaccine.2021.12.036

Cited by 1 publication

(1 citation statement)

References 12 publications

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“…This finding is in line with data from Brazil, where an important decline in mortality in adults aged ≥80 years was seen after the introduction of the COVID-19 vaccine ( 25 ). Studies in Canada, France, and Israel also showed that initial vaccination efforts directed at adults aged 65 years and older resulted in significant overall declines in COVID-19 cases and deaths, ranging from 21% to 80% in COVID-19 cases and 30% to 87% in COVID-19 deaths ( 10 , 26 , 27 ). Given the greater COVID-19 vaccine efficacy against hospitalization and death, further studies to evaluate the effect of COVID-19 vaccines on different clinical outcomes, such as mortality or hospitalization, in the general population would be useful to increase the evidence of the public health benefits of COVID-19 vaccination.…”

Section: Discussionmentioning

confidence: 99%

Early impact of COVID-19 vaccination on older populations in four countries of the Americas, 2021

Jarquín

Quezada

Gobern

et al. 2023

Revista Panamericana De Salud Pública

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Objective. To estimate the early impact of coronavirus disease 2019 (COVID-19) vaccination on cases in older populations in four countries (Chile, Colombia, Guatemala, and the United States of America), and on deaths in Chile and Guatemala. Methods. Data were obtained from national databases of confirmed COVID-19 cases and deaths and vaccinations between 1 July 2020 and 31 August 2021. In each country, pre- and post-vaccination incidence ratios were calculated for COVID-19 cases and deaths in prioritized groups (50–59, 60–69, and ≥70 years) compared with those in the reference group (<50 years). Vaccination effect was calculated as the percentage change in incidence ratios between pre- and post-vaccination periods. Results. The ratio of COVID-19 cases in those aged ≥50 years to those aged <50 years decreased significantly after vaccine implementation by 9.8% (95% CI: 9.5 to 10.1%) in Chile, 22.5% (95% CI: 22.0 to 23.1%) in Colombia, 20.8% (95% CI: 20.6 to 21.1%) in Guatemala, and 7.8% (95% CI: 7.6 to 7.9%) in the USA. Reductions in the ratio were highest in adults aged ≥70 years. The effect of vaccination on deaths, with time lags incorporated, was highest in the age group ≥70 years in both Chile and Guatemala: 14.4% (95% CI: 11.4 to 17.4%) and 37.3% (95% CI: 30.9 to 43.7%), respectively. Conclusions. COVID-19 vaccination significantly reduced morbidity in the early post-vaccination period in targeted groups. In the context of a global pandemic with limited vaccine availability, prioritization strategies are important to reduce the burden of disease in high-risk age groups.

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