COVID-19 vaccine – technical aspects of vaccination

Jaciubek, Marzena; Prasek, Karolina

doi:10.2478/pielxxiw-2021-0009

Cited by 4 publications

(3 citation statements)

References 3 publications

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“…Now, one of the main weapons that has proved able to fight the virus [ 6 ] in an effective way is the vaccine against SARS-CoV-2 [ 6 ]. Nevertheless, the vaccination rate is not satisfactory in some countries [ 7 , 8 ], due to people’s refusal to receive one of the approved vaccines or booster doses [ 9 ].…”

Section: Introductionmentioning

confidence: 99%

Survey upon the Reasons of COVID-19 Vaccination Acceptance in Romania

2022

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Aim: The present study aims to observe the reasons for which the participants have chosen to uptake one of the COVID-19 vaccines approved in Romania. Thus, it will help us to determine whether the reasons are medical in nature, with the respondents’ scope to stay healthy, or if there are other motivations. High rates of vaccine acceptance are essential in the struggle against the COVID-19 pandemic, and trust indicators in other inoculations may be vital for the good management of the vaccination campaign. Methods: The research consisted in applying an online questionnaire in the period January–March 2022 during the fifth wave of COVID-19. The individuals in the target group had to comply with three conditions: they should be inoculated, at least 18 years of age and Romanian residents. The questionnaire was administered to 2297 people and structured to obtain socio-demographic data, determine confidence in mandatory and optional vaccines (rotavirus, hepatitis A, meningococcal vaccine, etc.) and extract the reasons why respondents chose to be vaccinated. Results: The data extracted from the questionnaire reveal a high rate of confidence of participants in the vaccines included in the national vaccination scheme (98.6%) and in the optional vaccines other than anti-COVID-19 (97.2%). Of the respondents, 23.4% had at least one positive test for COVID-19. Although the entire sample is vaccinated against the SARS-CoV-2 virus, the reasons behind the decision to vaccinate are not only medical in nature, thus, 18.3% were motivated by “protecting their own health/protection against the virus”, 17% due to “fear of the disease”, 8.8% for getting back to normal life and ending the pandemic and 8.5% due to government restrictions/vaccination certificate. Conclusions: In our study, we were able to validate the research hypothesis that the reasons for vaccine acceptance are multiple and not only medical (health protection, existing co-morbidities, etc.) and to show that although vaccination has been accepted, some participants believe in conspiracy theories, including those that try to convince people of the harmfulness of the vaccine. In addition, by applying Pearson, Kendall and Spearman correlation tests, we observed that indicators showing high confidence in optional vaccines relate strongly with the decision to vaccinate against COVID-19.

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Section: Introductionmentioning

confidence: 99%

Survey upon the Reasons of COVID-19 Vaccination Acceptance in Romania

2022

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“…The bases of these vaccines are diverse and some of the approved ones are based on new technology platforms (Yoo 2021), speci cally, they are nucleotide-based. Nucleotide-based vaccines (NBVs) offer a relatively quick production cycle (Jaciubek and Prasek 2021) Their main strategy is to exploit the molecular machinery responsible for protein synthesis in the cells to produce a viral protein, which is presented on the cell surface and, in turn, stimulates an effective immune response (Kowalczyk et al 2016) (Ho et al 2021).…”

Section: Introductionmentioning

confidence: 99%

Healthcare workers' Attitude and Knowledge Towards the Safety of Nucleotide-Based Vaccines.

Madadha

Ahmed

Rayyan

et al. 2021

Preprint

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Background and objectives: With the implementation of nucleotide-based vaccines (NBVs) in the COVID-19 vaccination campaigns, a wide controversy surrounding NBVs has become a heated subject of debate, and it did not spare healthcare workers and staff. The latter group has a powerful influence on the acceptance of NBVs by the general public. Hence, the aim of this study to assess the knowledge and attitude of healthcare workers regarding this new vaccine technology.Methods: This is a cross-sectional study using an online survey involving health workers in Jordan. The survey assessed the participants' socio-demographic characteristics, knowledge, and attitude about the safety and efficacy if NBVs. The study population was divided into two groups, educated and uneducated groups, whereby the former received a small educational pamphlet on NBVs. The Mann-Whitney test was used to compare between the response of the two groups.Results: A total of 330 health workers participated in this study. Respondents believed that RNA-based NBVs would be a safer option compared to DNA-based ones, with the educated group showing significant difference. The notion of NBVs being a form of gene therapy was more common among the educated group. The majority of the participants, particularly amongst the uneducated group, were concerned about undiscovered effects of NBVs. Respondents also agreed that NBVs must be reevaluated in phase 1 trials. As for efficacy, our study population agreed that these vaccines would prevent severe illness. Conclusions: Although healthcare workers have positive knowledge and attitude towards NBVs, misconceptions and skepticism exist and must be addressed with more education efforts.

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“…Nucleotide-based vaccines (NBVs) offer a relatively quick production cycle [15] Their main strategy is to exploit the molecular machinery responsible for protein synthesis in the cells to produce a viral protein, which is presented on the cell surface and, in turn, stimulates an effective immune response [16] [17].…”

Section: Introductionmentioning

confidence: 99%

Comparision Study On The Knowledge and Attitude Between Healthcare Workers Based On Educational materials of Nucleotie Based Vaccines

Madadha¹,

Ahmed

Rayyan

et al. 2021

Preprint

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Background With the implementation of nucleotide-based vaccines (NBVs) in the COVID-19 vaccination campaigns, a wide controversy surrounding NBVs has become a heated subject of debate, and it did not spare healthcare workers (HCW) and staff. HCW have a powerful influence on the acceptance of NBVs by the general public. Hence, the aim of this study was to assess the knowledge and attitude of healthcare workers regarding this new vaccine technology. Methods This is a cross-sectional study using an online survey involving health workers in Jordan. The survey assessed the participants' socio-demographic characteristics, knowledge, and attitude about the safety and efficacy if NBVs. The study population was divided into two groups, educated and uneducated groups, whereby the former received a small educational pamphlet on NBVs. The Mann-Whitney test was used to compare between the response of the two groups. Results A total of 330 health workers participated in this study. Respondents believed that RNA-based NBVs would be a safer option compared to DNA-based ones, with the educated group showing significant difference. The notion of NBVs being a form of gene therapy was more common among the educated group. The majority of the participants, particularly amongst the uneducated group, were concerned about undiscovered effects of NBVs. Respondents also agreed that NBVs must be reevaluated in phase 1 trials. As for efficacy, our study population agreed that these vaccines would prevent severe illness. Conclusions Although healthcare workers have positive knowledge and attitude towards NBVs, misconceptions and skepticism exist and must be addressed with more education efforts.

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COVID-19 vaccine – technical aspects of vaccination

Cited by 4 publications

References 3 publications

Survey upon the Reasons of COVID-19 Vaccination Acceptance in Romania

Survey upon the Reasons of COVID-19 Vaccination Acceptance in Romania

Healthcare workers' Attitude and Knowledge Towards the Safety of Nucleotide-Based Vaccines.

Comparision Study On The Knowledge and Attitude Between Healthcare Workers Based On Educational materials of Nucleotie Based Vaccines

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