COVID-19: What do we know?

Marshall, Steve; Duryea, Michael; Huang, Greg J.; Kadioglu, Onur; Mah, James; Palomo, Juan Martín; Rossouw, Emile; Stappert, Dina; Stewart, Kelton T.; Tüfekçi, Eser

doi:10.1016/j.ajodo.2020.08.010

Cited by 5 publications

(3 citation statements)

References 118 publications

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“…Higher levels indicate a more severe infection, and such levels have been used as markers of the severity of COVID-19. Elevated levels of serum C-reactive protein have been observed in patients with COVID-19 and have been used to aid in the following triage: diagnosis of infection, quantification of inflammatory status, and prognosis of the patients [ 26 , 27 ]. Crucially, the levels can increase before a patient’s vital signs are affected or before the leukocytes are increased [ 6 , 27 ].…”

Section: Discussionmentioning

confidence: 99%

The Inflammatory Profile Correlates with COVID-19 Severity and Mortality in Cancer Patients

Budin,

Nemeș,

Râjnoveanu

et al. 2023

JPM

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Background: The correlation of the inflammatory profile with the severity of the disease in neoplastic patients with SARS-CoV-2 infection was addressed. Methods: A database of 1537 patients hospitalized in the pneumology department was analyzed. After applying the inclusion and exclusion criteria, 83 patients (67% males, 33% females) were included. Results: Most of the analyzed patients were hospitalized with a moderate form of disease, explaining the significant percentage of 25% mortality. The frequency of the type of neoplasm was higher for lung cancer, followed by malignant colon tumor. We identified a significant association between the increased value of ferritin (p < 0.0001, OR = 22.31), fibrinogen (p = 0.009, OR = 13.41), and C-reactive protein (p = 0.01, OR = 7.65), respectively, and the level of severity of COVID-19. The results of the univariate logistic regression analysis for predicting the severity of the disease revealed that the increased values of ferritin (p = 0.001, OR = 22.31) and fibrinogen (p = 0.02, OR = 13.41) represent a risk for a serious negative prognosis of COVID-19. Conclusions: Our study demonstrated that the value of the analyzed inflammatory parameters increased in direct proportion to the severity of the disease and that higher values were associated with increased mortality in the study group.

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Section: Discussionmentioning

confidence: 99%

The Inflammatory Profile Correlates with COVID-19 Severity and Mortality in Cancer Patients

Budin,

Nemeș,

Râjnoveanu

et al. 2023

JPM

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“…This disease is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); it rapidly spread throughout the world [ 2 ]. Owing to its rapid transmissibility (direct inhalation of airborne virus or indirect transfer to the mouth from surfaces contaminated with virus-laden salivary/respiratory secretions) [ 3 , 4 ], and the relatively high infection fatality rate (1.4–9.6%) [ 5 ], all social settings including medical service professions, especially dentistry, were significantly adversely affected. Public safety policy was promoted to limit dental and orthodontic care to only urgent/emergency treatment [ 4 ].…”

Section: Introductionmentioning

confidence: 99%

The Impact of the COVID-19 Pandemic on Israeli Orthodontic Practice: A Clinic’s Activity and Patients’ Attitudes

Tunis

Ratson

Matalon

et al. 2022

IJERPH

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The current study aimed to characterize the activity in orthodontic clinics during the COVID-19-induced lockdown and the inter-lockdown periods, as well as to evaluate patients’ perspectives with respect to their fears, their extent of cooperation with treatment, and their emergency needs during the lockdown. The data were gathered from 11 private orthodontic clinics from 1 January 2020 to 8 March 2021, which included three lockdowns and inter-lockdowns. Information specifying the number of admissions, missed appointments, and emergency visits was gathered. Four hundred and twenty-nine orthodontic patients treated in those clinics agreed to complete a questionnaire that evaluated their concerns and expectations, the treatment emergency issues, implementation of the orthodontist’s instructions, and contact with the clinical staff during lockdowns. There was a significant increase in the number of scheduled appointments during the inter-lockdown periods, compared with the pre-pandemic period (p = 0.001). No difference in the number of missed/canceled or emergency appointments was found between the different periods (p > 0.420). The majority (89.6%) of the emergency visits involved issues with appliances; 68.7% of the subjects were advised to present themselves at clinics. During the peaks of the waves of the COVID-19 pandemic, a sharp rise in the number of missed and urgent appointments was not found. Reducing the number of orthodontic emergencies may assist in reducing patient fears.

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“…3 Despite all these preventive measures, SARS-CoV-2 spread rapidly in 2020 and policy-making organizations were worried about halting this viral web. 4 Hence, the development and deployment of COVID-19 vaccines was considered to be the most promising health care fortification step to mitigate the rapid spread of the SARS-CoV-2 infection. 5 One of the greatest inventions of the 21 st century is the development of vaccination against life-threatening COVID-19.…”

Section: Introductionmentioning

confidence: 99%

Acceptance of SARS-CoV-2 vaccination and the associated factors among dental health care professionals: A cross-sectional survey

Qabool¹,

Hamid²,

Sukhia³

2022

Dent. Med. Probl.

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Background. One of the greatest inventions of the 21 st century is the development of vaccines against the life-threatening pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Whenever a new medication or treatment modality is introduced globally, it is accompanied by anxiety in the general public and among health care professionals.Objectives. The aim of the study was to explore factors that may influence the acceptance of COVID-19 vaccination among dental health care professionals, as they are the first subgroup in the population to receive the vaccine. Material and methods.A survey-based cross-sectional study was conducted on 164 health care professionals (general dentists, dental specialists with 2 years of experience after graduation and dental assistants). Data was collected by sending a URL link to the hard-and soft-copy questionnaire on Google Forms through all social media platforms. The questionnaire had 2 sections -the 1 st part concerned the demographic details and the 2 nd part was designed to assess the acceptance of SARS-CoV-2 vaccination among dental health care professionals and the related factors. The normality of the data was assessed with the Shapiro-Wilk test. The Cox regression algorithm was applied to evaluate the factors associated with the acceptance of SARS-CoV-2 vaccination.Results. Out of 164 participants, 85.37% showed a positive attitude toward vaccination and only 7.32% of dental health care professionals were not willing to get vaccinated; out of them, 5 were males and 7 were females. Those who refused to get vaccinated included 3.6% of general dentists, 21.1% of dental specialists and 11.7% of dental assistants. The complications of major concern were fever, myalgia and the lethargic condition immediately after vaccination. Conclusions.A small percentage of health care professionals declined to get vaccinated against COVID-19 and the main reason was uncertainty about the associated side effects. The respondents were mostly concerned about such side effects as fever, myalgia and the lethargic condition immediately after vaccination.

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COVID-19: What do we know?

Abstract: HIGHLIGHTS: Evidence regarding provision of orthodontic care during COVID-19 pandemic is examined

Cited by 5 publications

References 118 publications

The Inflammatory Profile Correlates with COVID-19 Severity and Mortality in Cancer Patients

The Inflammatory Profile Correlates with COVID-19 Severity and Mortality in Cancer Patients

The Impact of the COVID-19 Pandemic on Israeli Orthodontic Practice: A Clinic’s Activity and Patients’ Attitudes

Acceptance of SARS-CoV-2 vaccination and the associated factors among dental health care professionals: A cross-sectional survey

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