COVIDium: a COVID-19 resource compendium

Abstract

The severe acute respiratory syndrome coronavirus 2 that causes coronavirus disease 2019 (COVID-19) disrupted the normal functioning throughout the world since early 2020 and it continues to do so. Nonetheless, the global pandemic was taken up as a challenge by researchers across the globe to discover an effective cure, either in the form of a drug or vaccine. This resulted in an unprecedented surge of experimental and computational data and publications, which often translated their findings in the form of databases (DBs) and tools. Over 160 such DBs and more than 80 software tools were developed, which are uncharacterized, unannotated, deployed at different universal resource locators and are challenging to reach out through a normal web search. Besides, most of the DBs/tools are present on preprints and are either underutilized or unrecognized because of their inability to make it to top Google search hits. Henceforth, there was a need to crawl and characterize these DBs and create a compendium for easy referencing. The current article is one such concerted effort in this direction to create a COVID-19 resource compendium (COVIDium) that would facilitate the researchers to find suitable DBs and tools for their research studies. COVIDium tries to classify the DBs and tools into 11 broad categories for quick navigation. It also provides end-users some generic hit terms to filter the DB entries for quick access to the resources. Additionally, the DB provides Tracker Dashboard, Neuro Resources, references to COVID-19 datasets and protein–protein interactions. This compendium will be periodically updated to accommodate new resources. Database URL: The COVIDium is accessible through http://kraza.in/covidium/

Coronavirus Immunotherapeutic Consortium Database

“…Multiple resources that contain information about SARS-CoV-2-specific antibodies or provide details of literature studies describing these antibodies have been established ( 22 ). These include the Coronavirus Antibody Database ( 23 ), which has been compiling antibody information from the literature and patents since the beginning of the pandemic, and the Coronavirus Antiviral Research Database ( 24 ) that has a broader scope and also includes small molecule data.…”

COVIDanno, COVID-19 annotation in human

“…Currently, numerous in vitro models of multiple human tissues have been built to study COVID-19. To date, there are 11 COVID-19-related data resources and 4 databases that integrate publicly available COVID-19-related RNA-seq data ( Satyam et al, 2021 ). However, the knowledge obtained from these databases is limited, and a comprehensive analysis is lacking.…”

CoVM2: Molecular Biological Data Integration of SARS-CoV-2 Proteins in a Macro-to-Micro Method

“…Ahsan et al proposed OverCOVID [ 21 ], an integrative server including SARS-CoV-2-related databases, web servers, and tools. Satyam et al established COVIDium [ 22 ], which provided similar information, but also added PPI network data sets and classified all the data entries.…”