Craniofacial Implant Surgery

Sinn, Douglas P.; Bedrossian, Edmond; Vest, Allison

doi:10.1016/j.cden.2011.07.012

Cited by 11 publications

(16 citation statements)

References 28 publications

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“…In dental implant treatment, rapid and reliable osseointegration is the key to success [4,5], and the adhesion of epithelial cells over mesenchymal stem cells prohibits osseointegration [9,10,14,15]. Therefore, controlling the respective populations of epithelial and mesenchymal stem cells to shift the balance in favor of mesenchymal stem cells could help to ensure osseointegration.…”

Section: Discussionmentioning

confidence: 99%

“…However, for most patients, osseointegration is not rapid, and there is some delay between implantation of the titanium prosthetic and its osseointegration with the native bone [4,5]. Furthermore, some patients have insufficient bone for adequate implantation, and require surgical pre-treatment involving procedures such as autologous bone transplantation; these types of procedures are a significant burden to the patient [6,7,8].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Migration and Osteogenic Differentiation of Mesenchymal Stem Cells on Titanium with a Micro-Patterned Gelatin Matrix

Kawai¹,

Nagaoka²,

Inubushi³

et al. 2017

IJTAN

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Migration and Osteogenic Differentiation of Mesenchymal Stem Cells on Titanium with a Micro-Patterned Gelatin Matrix

Kawai¹,

Nagaoka²,

Inubushi³

et al. 2017

IJTAN

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“…Implant-retained [7,8] prosthesis prevents these complications and represents a comfortable and effective option for these patients. Age, gender and histology did not show any influence on implant outcomes.…”

Section: Discussionmentioning

confidence: 99%

Reconstruction of Mid-facial Defects Using Facial Prostheses Supported by Dental Implants

Cariati¹,

Solis²,

Perceval³

2016

J Aesthet Reconstr Surg

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A 63-year-old male patient presented to the outpatient department of our service with an ulcerated lesion which affected AbstractMalignant tumors which affect nasal structures are uncommon. They represent about 0.2% of all cancers and are more than twice as prevalent in males. Squamous cell carcinoma is the most common type of nasal cancer. However, basal cell carcinoma, melanoma, sarcoma and inverting papilloma can involve nose and/or para-nasal sinuses too. Although rare, these pathologies are the most frequent cause for acquired defects of the nose. In this light, the need to obtain clear resection margins obliges surgeon to perform extensive nose amputations. This report describes the case of a 63 years old man affected by squamous cell carcinoma of the nose. A total nose amputation was carried out due to the extension of the tumor. Nasal reconstruction was performed with an implant-retained prosthesis. Three dental implants were used for anchoring the nasal prostheses. This technology is safe and it ensures optimum esthetic results.

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“…Dental implants are very effective treatment for ecovering the occlusion after tooth loss [1,2,3]. However, in general, it takes long term for the osseointegration, it means the direct structural and functional connection between bone and the surface of the titanium of dental implants [4,5].…”

Section: Introductionmentioning

confidence: 99%

Cell Population of Mesenchymal Stem Cells on Micro-patterned Titanium

Kawai

Nagaoka²,

Yoshida

et al. 2017

Proceedings of the 2nd World Congress on Recent Advances in Nanotechnology

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-Dental implants are highly effective for improving the occlusion function after tooth loss. However, ordinarily titanium dental implants sometimes require long term for the osseointegration. If there is insufficient bone in the patients, surgical pre-treatment such as autologous bone transplantation is required, imposing a big burden on the patient. Furthermore, a predominance of invasion of the gingival epithelium by epithelial cells at an early stage increases the risk of unsuccessful osseointegration. Therefore, to reduce the burden on the patient and increase the success rate of dental implant treatment, we need to develop a dental implant that can promote osseointegration more quickly and efficiently. We presumed that it would be one of efficient strategies for the quick and reliable osseointegration if we could control the cell population around the dental implant. Here, we micro-patterned a titanium surface by using a gelatin matrix. Mesenchymal stem cells were cultured, and cell populations were investigated. On the titanium surface with a micro-patterned gelatin matrix, mesenchymal stem cells first adhered to the titanium and then to the gelatin, enabling cell adhesion to be controlled time dependently. These results suggest that it may be possible to develop functional dental implants in which we can control the cell population of epithelial and mesenchymal stem cells and can promote quick and reliable osseointegration.

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Craniofacial Implant Surgery

Cited by 11 publications

References 28 publications

Migration and Osteogenic Differentiation of Mesenchymal Stem Cells on Titanium with a Micro-Patterned Gelatin Matrix

Migration and Osteogenic Differentiation of Mesenchymal Stem Cells on Titanium with a Micro-Patterned Gelatin Matrix

Reconstruction of Mid-facial Defects Using Facial Prostheses Supported by Dental Implants

Cell Population of Mesenchymal Stem Cells on Micro-patterned Titanium

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