Crayfish <i>Procambarus clarkii</i> Retina and Nervous System Exhibit Antioxidant Circadian Rhythms Coupled with Metabolic and Luminous Daily Cycles

Fanjul‐Moles, María Luisa; Prieto-Sagredo, Julio; López, Dario Santiago; Bartolo, Ramón; Cruz-Rosas, Hugo I.

doi:10.1111/j.1751-1097.2008.00399.x

Cited by 26 publications

(27 citation statements)

References 28 publications

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“…Since then, GSH circadian oscillation has been confirmed in many studies across several different species, including rat, mouse, crayfish, and human (6,11,51,82). Further studies have shown that GSSG also shows daily patterns of expression, as well as the enzymes GPx, GR, and GST (1,6,11,37,42,100,109).…”

Section: Rhythmicity Of the Cellular Antioxidant System: Patterns Of mentioning

confidence: 83%

“…Several studies have shown evidence of differences in DNA damage, lipid peroxidation, and protein oxidation at different times of the day, thus indicating circadian oscillations of oxidative stress responses (51,90,97,100,176). These oscillations relate directly to the daily rhythm of antioxidant expression and protective enzyme activity levels (Fig.…”

Section: Rhythmicity Of the Cellular Antioxidant System: Patterns Of mentioning

confidence: 95%

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Circadian Rhythm Connections to Oxidative Stress: Implications for Human Health

Wilking

Ndiaye²,

Mukhtar³

et al. 2013

Antioxidants & Redox Signaling

246

192

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Significance: Oxygen and circadian rhythmicity are essential in a myriad of physiological processes to maintain homeostasis, from blood pressure and sleep/wake cycles, down to cellular signaling pathways that play critical roles in health and disease. If the human body or cells experience significant stress, their ability to regulate internal systems, including redox levels and circadian rhythms, may become impaired. At cellular as well as organismal levels, impairment in redox regulation and circadian rhythms may lead to a number of adverse effects, including the manifestation of a variety of diseases such as heart diseases, neurodegenerative conditions, and cancer. Recent Advances: Researchers have come to an understanding as to the basics of the circadian rhythm mechanism, as well as the importance of the numerous species of oxidative stress components. The effects of oxidative stress and dysregulated circadian rhythms have been a subject of intense investigations since they were first discovered, and recent investigations into the molecular mechanisms linking the two have started to elucidate the bases of their connection. Critical Issues: While much is known about the mechanics and importance of oxidative stress systems and circadian rhythms, the front where they interact has had very little research focused on it. This review discusses the idea that these two systems are together intricately involved in the healthy body, as well as in disease. Future Directions: We believe that for a more efficacious management of diseases that have both circadian rhythm and oxidative stress components in their pathogenesis, targeting both systems in tandem would be far more successful.

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Section: Rhythmicity Of the Cellular Antioxidant System: Patterns Of mentioning

confidence: 83%

Section: Rhythmicity Of the Cellular Antioxidant System: Patterns Of mentioning

confidence: 95%

Circadian Rhythm Connections to Oxidative Stress: Implications for Human Health

Wilking

Ndiaye²,

Mukhtar³

et al. 2013

Antioxidants & Redox Signaling

246

192

View full text Add to dashboard Cite

show abstract

“…However, in the two species P. clarkii and Procambarus digueti, the antioxidant systems are known to be very robust in their diel changes (270) and entrain to light phases (271). Especially the glutathione-system in the eyestalk and the brain of P. clarkii exhibits clear-cut circadian rhythmicity (272,273).…”

Section: Melatoninmentioning

confidence: 99%

Circadian clocks in crustaceans: identified neuronal and cellular systems

Strauß

Dircksen²

2010

Front Biosci

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Circadian rhythms are known for locomotory and reproductive behaviours, and the functioning of sensory organs, nervous structures, metabolism and developmental processes. The mechanisms and cellular bases of control are mainly inferred from circadian phenomenologies, ablation experiments and pharmacological approaches. Cellular systems for regulation summarised here comprise the retina, the eyestalk neuroendocrine X-organ-sinus gland system, several neuropeptides such as red pigment concentrating, hyperglycaemic and pigment-dispersing hormones, and factors such as serotonin and melatonin. No master clock has been identified, but a model of distributed clockwork involves oscillators such as the retinular cells, neurosecretory systems in the optic lobes, putative brain pacemakers, and the caudal photoreceptor. Extraretinal brain photoreceptors mediate entrainment. Comparative analyses of clock neurons and proteins known from insects may allow the identification of candidate clock neurons in crustaceans as putative homologues in the two taxa. Evidence for the existence of "insect-like" intracellular clock proteins and (light sensitive) transcription factors is scarce, but clock-, period-, and cryptochrome-gene products have been localised in the CNS and other organs rendering further investigations into crustacean clockwork very promising.

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“…In crustaceans, the synthesis of GSH occurs in the hepatopancreas and the gills, and synthesis of GSH is better with higher luminous intensity (Maciel et al 2004). With the growing number of redox reactions, the metabolism and production of reactive oxygen species (ROS) decrease glutathione levels (Fanjul-Moles et al 2009). The second reason is a steadily decreasing amount of polyunsaturated fatty acids.…”

Section: Introductionmentioning

confidence: 99%

“…The second reason is a steadily decreasing amount of polyunsaturated fatty acids. According to Fanjul-Moles et al (2009), the Procambarus clarkii membrane is very rich in phospholipids and PUFAs, and even low exposition to light as well as the lowest possibility of production of ROS induce a decrease in important components of the membrane and open up access into the organism (Balzer et al 1997). …”

Section: Introductionmentioning

confidence: 99%

The Use of Different MS Techniques to Determine Glutathione Levels in Marine Tissues

2012

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Several techniques were used, mainly mass spectrometry connected with gas chromatography, matrixassisted laser desorption with ionization time-of-flight and mass spectrometry connected with liquid chromatography. A major problem was encountered in determining glutathione, which can be conditioned by the pH and selected reducing agents. The GSH form can be oxidized through derivatization, and a small glutathione amount in the biological samples may hinder the determination process. Another problem is the existence of a metal ion in the tested organism; therefore, often a reagent with a chelating function is added to the sample and the mobile phase in liquid chromatography is applied with appropriate polarity for GSH and GSSG. We determined the concentrations of total, reduced, and oxidized glutathione in the liver, hepatopancreas, muscle, and gonad tissues of brown shrimp (Crangon crangon) and fish (Psetta maxima and Clupea harengus membras). The highest concentrations of tGSH were recorded in the shrimp hepatopancreas (7.21 ± 0.011 μmol g −1 wet weight), in herring liver (2.85±0.025 μmol g −1 ), and in turbot liver (1.86±0.063 μmol g −1). In turn, the highest concentrations were reported for GSSG in the muscle of shrimp (0.140±0.000204 μmol g ). We also investigated seasonal changes in the concentrations of glutathione in the muscle of C. crangon shrimp in the annual cycle. The lowest values of total glutathione were recorded during spring and autumn, which could be correlated with the increase in lipid peroxidation and oxidative stress.

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Crayfish Procambarus clarkii Retina and Nervous System Exhibit Antioxidant Circadian Rhythms Coupled with Metabolic and Luminous Daily Cycles

Cited by 26 publications

References 28 publications

Circadian Rhythm Connections to Oxidative Stress: Implications for Human Health

Circadian Rhythm Connections to Oxidative Stress: Implications for Human Health

Circadian clocks in crustaceans: identified neuronal and cellular systems

The Use of Different MS Techniques to Determine Glutathione Levels in Marine Tissues

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