Creatine kinase and C reactive protein as an indicator for tissue damage in the retained placenta in cows

Al-Watar, Barra D.; Lazim, E. H.; Al-Hyani, Osama H.

doi:10.33899/ijvs.2020.126496.1338

Cited by 4 publications

(5 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The present study reported that the incidence of retained placenta was nearly 10 % which is nearly the same 9% as reported by Purohit et al (14). The incidence rate of toxic puerperal metritis in this study was about 7%, which is much lower 17% reported by Azawi et al (12) in Iraqi cowsbuffalo. This study found that he incidence of uterine prolapse was 5.23%, which is lower than 7.73% reported by Purohit et al (14) in Pakistan.…”

Section: Discussionsupporting

confidence: 79%

“…The post-partum disorders were diagnosed on a routine veterinary visit (clinical signs and clinical examinations). The placenta was considered retained if the retention of the fetal membrane occurs within over 12 hours (11,12). Toxic puerperal metritis was diagnosed depending on the prevalence of the inflammation of uterine layers with enlarged uterus in the first 10-14 days after calving associated with general toxemia, red brown fetid uterine discharge, fever up to 39.5°C, and decrease of milk production (13).…”

Section: Methodsmentioning

confidence: 99%

See 1 more Smart Citation

Study on the post-partum disorders and their relationship with the reproductive performance in Iraqi cow-buffaloes

Rahawy¹

2021

IJVS

View full text Add to dashboard Cite

This study was conducted to evaluate the influence of various postpartum disorders on subsequent reproductive performance in Iraqi cow buffaloes. The data were collected from 172 buffaloes within private dairy buffaloes herd. In this study, the diagnosis and treatment of the affected cases with postpartum disorders (Retained placenta, puerperal metritis, uterine prolapse and vaginal prolapse) contributed in the data collection based on the parity, calving time and reproductive parameters (days to first estrus, open days, service per conception, intervals between estrus and calving interval). Cow buffaloes were divided according to their postpartum disorders into 5 groups: first group (healthy), second group (retained placenta), third group (puerperal metritis), forth group (uterine prolapse) and fifth (vaginal prolapse). The results of this study showed that a total of 74.42% of the cow buffaloes had normal post-partum and open days 121.9 days with resumed ovarian cyclic activity within 77.41 days, increased incidence of G2, G3, G4 and G5 were 9.88, 6.97, 6.97, 5.23 and 3.48%, respectively. Open days were significantly longer in buffaloes in groups 2, 3, 4 and 5 compared to healthy group. In conclusions, early postpartum disorders manifested by increased days to first estrus, calving interval, days open and service per conception were longer than healthy cases in the Iraqi cow-buffaloes.

show abstract

Section: Discussionsupporting

confidence: 79%

Section: Methodsmentioning

confidence: 99%

Study on the post-partum disorders and their relationship with the reproductive performance in Iraqi cow-buffaloes

Rahawy¹

2021

IJVS

View full text Add to dashboard Cite

show abstract

“…Serological tests are safe, rapid, and somewhat inexpensive diagnostic tools; Rose Bengal test, enzymelinked immunosorbent assays, complement fixation test is advisable tests for large-scale eradication objectives (21,22).…”

Section: Discussionmentioning

confidence: 99%

A cross sectional study on the seroprevalence of bovine brucellosis in Al-Najaf province in Iraq

Al-Alo¹,

Mohammed²

2021

IJVS

View full text Add to dashboard Cite

Brucellosis is an endemic disease in many countries of the middle east including Iraq, despite the high attempts to control the disease in animals using vaccination programs. The study was conducted from January to March 2012, to determine the prevalence of bovine brucellosis in the Al-Najaf province in Iraq, which represent risk factors associated with brucellosis in cattle. Blood samples were collected from 172 cows and 15 bulls of 20 dualpurpose cattle herds. Serological examinations are the most useful and widely used tool for the diagnosis of brucellosis in man and animals. All animal serum samples were tested by the Rose Bengal plate test (RBT), and the positive cases were confirmed by competitive enzyme-linked immunosorbent assay (c-ELISA). The overall prevalence of brucellosis was 5.81% divided between 5.81% in females and 0% in males, and 40% as herd numbers level. Females showed a higher seropositive reaction to the disease than males. In conclusion, this study demonstrated the presence of the disease and detected the seropositive reactions in animal samples in different farms of the province, with a difference in infection rate regarding the risk factor. Sanitary measures must be taken to avoid the occurrence and spread of the disease in humans and animals.

show abstract

“…Acute phase proteins, primarily CRP, are more concentrated in retained fetal membranes when mastitis and endometritis are present. This is because lymphocytes and macrophages in retained fetal membranes secrete more IL-6, which causes CRP to bind to the surface of dying cells and make it easier for macrophages to phagocytose these cells, reducing the risk of infection and inflammation in the placental tissue [22,23]. Activated macrophages, natural killer cells, and T lymphocytes create tumor necrosis factoralpha (TNF-α), a pleiotropic cytokine that regulates inflammation and is elevated in serum and placental tissue [24].…”

Section: Discussionmentioning

confidence: 99%

The effect of inflammatory cytokines on occurrence of retained placenta in cattle

Dhaher,

Eesa,

Al-Mutar

et al. 2024

Adv. life sci.

View full text Add to dashboard Cite

Background: In simple terms, retained placenta is a common issue after parturition in cattle that can affect their reproductive ability. In pregnancies with fetal growth restriction (FGR), the placenta has low anti-inflammatory cytokines and high pro-inflammatory cytokines. By looking at variations in cytokine levels in the blood, we can diagnose the condition. The focus of a recent study was to examine the role of some interleukins (Interleukins -10, Interleukins -6, Interleukins -1β), C-reactive protein (CRP) and Tumor Necrosis Factor (TNF)-α, in retained placenta occurrence in cattle.Methods: The study involved 40 cows, aged 3-8 years in the Salah-Din province. Each animal suffered from retained placenta also eleven healthy cows served as the control group in a period of January to August 2022. The blood serum was analyzed using enzyme immunoassay techniques (ELIZA) to measure the levels of IL-10, IL-6, IL-1β, CRP and TNF-α.Results: Serum levels of IL-10, IL-6, IL-1β, CRP and TNF-α showed a significant increase in cows experiencing retained fetal membranes compared to healthy cows (2.31±0.11 vs 1.41 ±0.07) (10.48±0.24 vs 5.40±0.19), (13.6±2.1 vs 4±0.9), (0.9±0.02 vs 0.32±0.04) and (60.1 ± 12.79 vs 29.5 ± 16.58) respectively.Conclusion: from the present study we conclude that IL10, IL6, IL1β and TNFα play an essential component in retained placenta incidence, and the estimation levels of these parameters in serum may be considered good indicator for occurrence in cattle. RT-PCR revealed increased expression of SDHA genes in the maternal compartment of the placenta.Keywords: Retained placenta; Cytokines; C-reactive protein

show abstract

Creatine kinase and C reactive protein as an indicator for tissue damage in the retained placenta in cows

Cited by 4 publications

References 19 publications

Study on the post-partum disorders and their relationship with the reproductive performance in Iraqi cow-buffaloes

Study on the post-partum disorders and their relationship with the reproductive performance in Iraqi cow-buffaloes

A cross sectional study on the seroprevalence of bovine brucellosis in Al-Najaf province in Iraq

The effect of inflammatory cytokines on occurrence of retained placenta in cattle

Contact Info

Product

Resources

About