Creation of Hierarchical Polysaccharide Strand: Supramolecular Spinning of Nanofibers by Microfluidic Device

Numata, Munenori; Takigami, Yusuke; Takayama, Momoko

doi:10.1246/cl.2011.102

Cited by 11 publications

(2 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…These results support the view that a liquid/liquid interface can act as a template for the creation of supramolecular structures of SPG 7. Based on these previous experimental results, in the present system, the dynamic liquid/liquid interface that is generated in a microfluidic channel also acts as an effective template for the self‐assembly of s‐SPG 8a…”

Section: Resultssupporting

confidence: 89%

Hierarchical Supramolecular Spinning of Nanofibers in a Microfluidic Channel: Tuning Nanostructures at a Dynamic Interface

Numata

Takigami

Takayama

et al. 2012

Chemistry A European J

Self Cite

View full text Add to dashboard Cite

One of the fundamental problems in supramolecular chemistry, as well as in material sciences, is how to control the self-assembly of polymers on the nanometer scale and how to spontaneously organize them towards the macroscopic scale. To overcome this problem, inspired by the self-assembly systems in nature, which feature the dynamically controlled self-assembly of biopolymers, we have previously proposed a self-assembly system that uses a dynamic liquid/liquid interface with dimensions in the micrometer regime, thereby allowing polymers to self-assemble under precisely controlled nonequilibrium conditions. Herein, we further extend this system to the creation of hierarchical self-assembled architectures of polysaccharides. A natural polysaccharide, β-1,3-glucan (SPG), and water were injected into opposite "legs" of microfluidic devices that had a Y-shape junction, so that two solvents would gradually mix in the down stem, thereby causing SPG to spontaneously self-assemble along the flow in a head-to-tail fashion, mainly through hydrophobic interactions. In the initial stage, several SPG nanofibers would self-assemble at the Y-junction owing to the shearing force, thereby creating oligomers with a three-way junction point. This unique structure, which could not be created through conventional mixing procedures, has a divergent self-assembly capability. The dynamic flow allows the oligomers to interact continuously with SPG nanofibers that are fed into the Y-junction, thus amplifying the nanostructure along the flow to form SPG networks. Consequently, we were able to create stable, centimeter-length macroscopic polysaccharide strands under the selected flow conditions, which implies that SPG nanofibers were assembled hierarchically in a supramolecular fashion in the dynamic flow. Microscopic observations, including SEM and AFM analysis, revealed the existence of clear hierarchical structures inside the obtained strand. The network structures self-assembled to form sub-micrometer-sized fibers. The long fibers further entangled with each other to give stable micrometer-sized fibers, which finally assembled to form the macroscopic strands, in which the final stabilities in the macroscopic regime were governed by that of the network structures in the nanometer regime. Thus, we have exploited this new supramolecular system to create hierarchical polymeric architectures under precisely controlled flow conditions, by combining the conventional supramolecular strategy with microfluidic science.

show abstract

Section: Resultssupporting

confidence: 89%

Hierarchical Supramolecular Spinning of Nanofibers in a Microfluidic Channel: Tuning Nanostructures at a Dynamic Interface

Numata

Takigami

Takayama

et al. 2012

Chemistry A European J

Self Cite

View full text Add to dashboard Cite

show abstract

“…In previous studies, we exploited the possibility of using a microflow channel as a designable flowing field for the self‐assembly of functional molecules3c, d and polymers 3a. b We have found that microfluidic systems enable us to tune intermolecular (or interpolymer) interactions in a way that is different form that encountered in thermodynamic self‐assembly processes; it can amplify the resultant nanostructures along the continuous flow, leading finally to the creation of novel supramolecular architectures that would never be accessible through conventional self‐assembly.…”

mentioning

confidence: 99%

Two‐Dimensional Assembly Based on Flow Supramolecular Chemistry: Kinetic Control of Molecular Interactions Under Solvent Diffusion

Numata

Kozawa

2014

Chemistry A European J

Self Cite

View full text Add to dashboard Cite

show abstract

Multifunctional Micro/Nanoscale Fibers Based on Microfluidic Spinning Technology

2019

Advanced Materials

194

174

View full text Add to dashboard Cite

Superfine multifunctional micro/nanoscale fibrous materials with high surface area and ordered structure have attracted intensive attention for widespread applications in recent years. Microfluidic spinning technology (MST) has emerged as a powerful and versatile platform because of its various advantages such as high surface‐area‐to‐volume ratio, effective heat transfer, and enhanced reaction rate. The resultant well‐defined micro/nanoscale fibers exhibit controllable compositions, advanced structures, and new physical/chemical properties. The latest developments and achievements in microfluidic spun fiber materials are summarized in terms of the underlying preparation principles, geometric configurations, and functionalization. Variously architected structures and shapes by MST, including cylindrical, grooved, flat, anisotropic, hollow, core–shell, Janus, heterogeneous, helical, and knotted fibers, are emphasized. In particular, fiber‐spinning chemistry in MST for achieving functionalization of fiber materials by in situ chemical reactions inside fibers is introduced. Additionally, the applications of the fabricated functional fibers are highlighted in sensors, microactuators, photoelectric devices, flexible electronics, tissue engineering, drug delivery, and water collection. Finally, recent progress, challenges, and future perspectives are discussed.

show abstract

Creation of Hierarchical Polysaccharide Strand: Supramolecular Spinning of Nanofibers by Microfluidic Device

Cited by 11 publications

References 4 publications

Hierarchical Supramolecular Spinning of Nanofibers in a Microfluidic Channel: Tuning Nanostructures at a Dynamic Interface

Hierarchical Supramolecular Spinning of Nanofibers in a Microfluidic Channel: Tuning Nanostructures at a Dynamic Interface

Two‐Dimensional Assembly Based on Flow Supramolecular Chemistry: Kinetic Control of Molecular Interactions Under Solvent Diffusion

Multifunctional Micro/Nanoscale Fibers Based on Microfluidic Spinning Technology

Contact Info

Product

Resources

About