Cribado de infecciones cervicales de transmisión sexual en mujeres embarazadas y su relación con la microbiota vaginal

Abstract

Screening of cervical sexually transmitted infections in pregnant women and the relation with the vaginal microbiota Background: Pregnant woman is exposed to many sexual transmitted infections (STI). Many of these infections may produce diseases in the fetus and newborn, and also alteration in the normal course of the pregnancy. Aim: Screening of asymptomatic cervical infection in pregnant woman and its relationship with the vaginal microbiota. Patients and Methods: 85 pregnant women without clinical cervicitis who consult in the routine pregnant control (47 patients) and women derived from STI service (38 patients). The samples were obtained from the vaginal fund sac and were analyzed with optic microscopy, cultures and PCR of Neisseria gonorrhoeae, Trichomonas vaginalis and Chlamydia trachomatis. Results: 12,9% of the enrolled women were positive for C. trachomatis, 2,4% for T. vaginalis. In this study, we did not found N. gonorrhoeae. We observed 23,3% of patients with altered microbiota (bacterial vaginosis and intermediate microbiota) was positive for C. trachomatis. Conclusions: In this study, we found a high frequency of C. trachomatis infection, that correlates with the presence of altered microbiota. This high frequency would promote preventive strategies in the pregnant women routine controls.

Prevalencia de la infección por Chlamydia trachomatis y su potencial impacto perinatal en pacientes chilenas

“…Entre los estudios realizados exclusivamente en mujeres embarazadas, Palma y cols., (2019) 20 evaluaron la frecuencia de infecciones cervicales en gestantes. Se incluyeron 85 mujeres, de ellas 47 asistían a su control de rutina, sin ITS asociada, y 38 fueron derivadas con ITS asociada (principalmente condilomas acuminados y molusco).…”

“…En un estudio reciente de Palma y cols., del año 2018, la prevalencia en mujeres gestantes (12,9%) 20 es mucho mayor respecto de un estudio realizado por Ovalle y cols., seis años antes, quienes analizaron muestras endocervicales de 258 mujeres embarazadas y reportaron una prevalencia de 5,9% 21 .…”