Cristatumins A–D, new indole alkaloids from the marine-derived endophytic fungus Eurotium cristatum EN-220

Synthetic and Structure-Activity Relationship Studies on Bioactive Natural Products

“…Bridelia ferruginea (Euphorbiaceae), 45) Eurotium sp., [46][47][48][49] Penicillium griseofulvum, 50) and the aerial parts of Plumbago zeylanica.…”

Indolediketopiperazine Alkaloids from Eurotium cristatum EN-220, an Endophytic Fungus Isolated from the Marine Alga Sargassum thunbergii

“…Most of the algicolous fungi distributed in the genera of Aspergillus and Penicillium , which belong to the facultative marine fungi that were frequently discovered from different groups of algae [1,2]. However, four strains of the fungal genus Eurotium including E. cristatum [3], E. rubrum [4], Eurotium sp. [5], and E. herbariorum [6], have been characterized from the brown alga of Sargassum thunbergii [3], red alga of Asparagopsis taxiformis [4] and Bostrychia tenella [5], and green alga of Epiactis prolifera [6].…”

New prenylated indole alkaloids from fungus Penicillium sp. derived of mangrove soil sample

“…Some of these compounds showed tremor-producing, cytotoxic, antibacterial, and brine shrimp lethal activity [3][4][5][6][7]. In our continuing investigation aimed to explore new and bioactive secondary metabolites from marine-derived fungi [9][10][11][12][13][14][15], we recently focused on a fungal strain Penicillium brefeldianum SD-273 that was isolated from the sediment samples collected from the estuary of the Pearl River in the South China Sea.…”

“…Indolediketopiperazine alkaloids are a series of natural occurring secondary metabolites generally formed from L-tryptophan and other common amino acids, e.g., L-proline, L-alanine, and D-valine [1][2][3][4][5][6][7][8].…”