Criterion for evaluation and optimization in thin-layer chromatography

Abstract

commercially available sorbent tubes. Based on the experimental conditions and results, the tubes containing Tenax would be preferred for sampling of the four amines. For field applications, the sorbents should be further evaluated at air temperatures above 22 °C and over a wider range of humidity. ACKNOWLEDGMENTHelpful comments on the paper by D. T. Williams and R. P. Moody are gratefully acknowledged.

Pharmaceuticals and Drugs

“…Similarly, overlapping resolution maps were used as a criterion by Issaq et al (71) and by Nurok et al (72), who extended this approach to continuous development. Application of the sequential simplex method was also reported (73,74).…”

Theory of Retention in Reversed Phase Liquid Chromatography with Ternary Mobile Phases

“…The choice of a mobile phase for a given separation is still a difficult task. Various systematic strategies have been proposed for the selection of suitable solvents. ,, The fundamental theoretical results have been published by Schoenmakers et al Certain aspects of retention in multicomponent mobile phases have been previously analyzed but without any concrete solutions and applications . The equations describing retention in such systems are relatively complicated and may be difficult to use by a practicing chromatographer.…”

Optimization

“…7) (18), multispot response function (Eq. 8) (19), separation response (Eq. 9) (20), chromatographic response function (Eq.…”