Pharmaceuticals and Drugs

Nyiredy, Szabolcs; V√©gh, Zoltan; Szepesi, G√°bor; Ferenczi-Fodor, K.

doi:10.1201/9780203912430.ch28

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Cited by 2 publications

(2 citation statements)

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“…Since pharmaceutical and biomedical analysis is undoubtedly the most important application field of TLC, even general textbooks dealing with this technique contain a wealth of information on these issues [73][74][75][76]. TLC is a widely used technique in pharmaceutical and biomedical analysis because of its ease of use, speed of separation, cost-effectiveness, and good detection power, as well as of its ability to analyze multiple samples simultaneously.…”

Section: Tlcmentioning

confidence: 99%

The Role of Analytical Chemistry in the Safety of Drug Therapy

Gǒrög

2012

Analytical Techniques for Clinical Chemistry

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Section: Tlcmentioning

confidence: 99%

The Role of Analytical Chemistry in the Safety of Drug Therapy

Gǒrög

2012

Analytical Techniques for Clinical Chemistry

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“…The number of publications in the field of pharmacy have been steadily increasing. [1,2] Many phenol derivatives have definite pharmacological and biological properties. Ibuprofen is a non-steroidal anti-inflammatory drug.…”

Section: Introductionmentioning

confidence: 99%

Comparison of Np-TLC and Rp-TLC With Densitometry to Quantitative Analysis of Ibuprofen in Pharmaceutical Preparations

Pyka

Bocheńska

2010

Journal of Liquid Chromatography & Related Technologies

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& NP-TLC and RP-TLC techniques with densitometry have been established for the identification and the quantification of ibuprofen in selected pharmaceutical preparations, namely: Nurofen, Ibuprom, and Ibum. Analyses were performed on silica gel 60 F 254 plates using n-hexane-ethyl acetate-acetic acid, 15:5:0.7, v=v (NP-TLC) and on RP18 F 254s plates using methanol-water, 9:1, v=v (RP-TLC). UV densitometry was performed at 200 and 224 nm for NP-TLC and RP-TLC analysis, respectively. NP-TLC and RP-TLC techniques with the densitometry and the spectrodensitometry applied to the investigation and the determination of ibuprofen in pharmaceutical preparations are selective, precise, and accurate. The techniques also realize the criterion of the linearity in the required range of ibuprofen concentrations.

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Pharmaceuticals and Drugs

Cited by 2 publications

References 63 publications

The Role of Analytical Chemistry in the Safety of Drug Therapy

The Role of Analytical Chemistry in the Safety of Drug Therapy

Comparison of Np-TLC and Rp-TLC With Densitometry to Quantitative Analysis of Ibuprofen in Pharmaceutical Preparations

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