Criterion-related validity of Cognistat in a primary care population

Aim To investigate the effectiveness of a semantic-based memory-encoding strategy intervention and cognitive stimulation that enhances function for older adults with mild cognitive impairment. Methods A two-armed single-blind non-randomised cluster controlled trial was conducted. Participants in two centres were allocated to the semantic-based memory-encoding experimental group and those in the other two centres received cognitive stimulation. In both groups, one centre- or community-based session and one home-based session were provided weekly for 10 weeks. Outcome measures included attention, memory and general cognitive function (Word List Memory and Word List Recall of the Consortium to Establish a Registry for the Alzheimer’s disease, Digit Span Forwards and Backwards and the Cognistat), and daily task performance (Disability Assessment for Dementia and Lawton Instrumental Activities of Daily Living Scale). They were administered pre- and post-intervention. Results Thirty-nine participants completed the study. No significant differences were revealed in the demographic or baseline data. The experimental group showed significant improvements in daily task performance (Disability Assessment for Dementia; p = 0.003), memory outcomes (Word List Recall; p < 0.001), general cognitive function (Cognistat subtests of Memory and Similarity; ps = 0.002 and < 0.001). The cognitive stimulation control group did not show any significant improvement in the measures. Between-group analysis showed significant differences in favour of the experimental group for the outcome measures of the Word List Recall and Cognistat Similarity subtest (ps < 0.001). Conclusions This study shows that the semantic-based memory-encoding strategy is more superior than cognitive stimulation with improvements in attention, memory, general cognitive function and daily task performance for people with a mild cognitive impairment. Trial registration ClinicalTrials.gov Protocol Registration and Results System (NCT02953964).

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“…Evidence indicates that it is sensitive to normal ageing [ 26 ]. The Cognistat has good validity for detecting cognitive impairment [ 27 ].…”

Section: Methodsmentioning

confidence: 99%

Semantic-based memory-encoding strategy and cognitive stimulation in enhancing cognitive function and daily task performance for older adults with mild cognitive impairment: A pilot non-randomised cluster controlled trial

Mraz

Tong²,

Liu³

2023

PLoS ONE

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“…Sedentary behaviour is any character outside of bedtime that is indicated by the energy expenditure of ≤ 1.5 METs, including sitting, half lying down, or lying down [11]. METs is a unit that expresses the amount of energy released from a specific activity [1]. The 2013 Basic Health Research obtained the results of the proportion for the population with sedentary behaviour.…”

Section: Sedentary Behaviourmentioning

confidence: 99%

“…Cognition is the process of identifying, selecting, interpreting, filtering, and using information that makes sense [1]. Meanwhile, impaired cognitive function in adulthood is associated with decreased functioning of daily activities.…”

Section: Introductionmentioning

confidence: 99%

“…Presently, BMI is one of the anthropometric indices that are still used to determine a person's nutritional status [11]. According to the Basic Health Research in 2013, the prevalence of underweight adults was 8.7 %, overweight by 13.5%, and obesity by 15.4% [8], while the Ministry of Health in 2013 also stated that the adult age group above 18 years was dominated by obesity and malnutrition problems which were still high [1].…”

Section: Introductionmentioning

confidence: 99%

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Review of the Effect of Sedentary Behaviour and BMI on Cognitive Decline in Young Adults

Putri¹,

Imran²

2023

Proceedings of the 3rd Borobudur International Symposium on Humanities and Social Science 2021 (BIS-HSS 2021)

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Cognition is the process of identifying, selecting, interpreting, filtering, and using information that makes sense. It encompasses a complex function concerning the domains of memory, executive, attention, perception, language, and psychomotor. Consequently, impaired cognitive function in adulthood might potentially lead to a decrease in the function of daily activities, increase the injury risk, require the attention of caregivers, and increase death risk. In adulthood, this function is affected by education level, physical activity, sedentary behaviour, stress, disease history, history of head injury, and Body Mass Index (BMI). Physical activity plays an important role in brain health across all age groups, specifically among young adults, which is the peak of changes in certain cognitive abilities. Furthermore, it consists of sedentary behaviour, as well as very mild, mild, moderate, heavy, and very heavy physical activity. Watching television, sitting in front of a computer, driving a vehicle, sitting at work, playing, sitting while listening to songs are physical activities that include sedentary behaviour. Prolonged sedentary time potentially affects areas of cognitive function causing weaker executive function and slower processing speed. Currently in Indonesia, the adult age group above 18 years is still dominated by obesity and malnutrition problems. Meanwhile, both high BMI and obesity are associated with low-grade chronic inflammation and elevated pro-inflammatory cytokines, which explains the detrimental effects of cognitive function. This indicates a high BMI causes lower cognitive performance in the areas of attention and impulsivity compared to individuals with a normal value. The purpose is to review the effect of sedentary behaviour and BMI on-cognitive decline in-young adults. Journal searches are conducted by researchers by looking from various sources such as PubMed / NCBI, google scholar, science direct by entering the initial keyword sedentary behaviour, which is then followed by other keywords namely cognitive, body mass index, and young, adults. The result of this review is the effect of sedentary behaviour on the cognitive decline is due to different physiological responses at the molecular level in obese individuals or others with excess BMI which decreases cognitive function through several mechanisms such as low-grade chronic inflammation, brain structural changes, and changes in leptin levels. Conclusion based on a literature review is sedentary behaviour and higher BMI can decline the cognitive function.

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Criterion-related validity of Cognistat in a primary care population

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Semantic-based memory-encoding strategy and cognitive stimulation in enhancing cognitive function and daily task performance for older adults with mild cognitive impairment: A pilot non-randomised cluster controlled trial

Semantic-based memory-encoding strategy and cognitive stimulation in enhancing cognitive function and daily task performance for older adults with mild cognitive impairment: A pilot non-randomised cluster controlled trial

Review of the Effect of Sedentary Behaviour and BMI on Cognitive Decline in Young Adults

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