Mobility degradation due to generation of interface traps (Δμ eff (N IT )) is a well-known phenomenon that has been theoretically interpreted by several mobility models. Based on these analysis, there is a general perception that Δμ eff (N IT ) is relatively insignificant (compared to Δμ eff due to ionized impurity) and as such can be safely ignored for performance and reliability analysis. Here, we investigate the importance of considering Δμ eff (N IT ) for reliability analysis by analyzing a wide variety of plasma oxynitride PMOS devices using both parametric and physical mobility models. We find that contrary to popular belief this correction is fundamentally important for robust and uncorrupted estimates of the key reliability parameters like threshold-voltage shift, lifetime projection, voltage acceleration factor, etc. Therefore, in this paper, we develop a generalized algorithm for estimating Δμ eff (N IT ) for plasma oxynitride PMOS devices and systematically explore its implications for NBTI-specific reliability analysis.