Critical Evaluation of Fine Needle Aspiration Cytology as a Diagnostic Technique in Bone Tumors and Tumor-like Lesions

Chakrabarti, Sudipta; Datta, Adrija; Hira, Michael

doi:10.7314/apjcp.2012.13.7.3031

Cited by 7 publications

(8 citation statements)

References 23 publications

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“…One area in which FNA has met continued skepticism is the evaluation of mesenchymal and soft tissue lesions, including those occurring in the bone. In this report, we have confirmed FNA as a valuable, highly sensitive technique (92% sensitivity) for the diagnosis of bone lesions …”

Section: Discussionsupporting

confidence: 64%

Diagnostic utility of fine‐needle aspiration cytology of lesions involving bone

Maisel

Frank

et al. 2017

Diagnostic Cytopathology

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Our findings indicate that FNA of bone lesions is a useful diagnostic technique with high sensitivity, particularly when the cytologic findings are interpreted in conjunction with the core biopsy and pertinent clinical and radiologic findings. In addition, ROSE followed by open, dynamic communication with the performing radiologist leads to an extremely low rate of inadequate core biopsy specimens, resulting in optimal patient diagnosis and management. Diagn. Cytopathol. 2017;45:608-613. © 2017 Wiley Periodicals, Inc.

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Section: Discussionsupporting

confidence: 64%

Diagnostic utility of fine‐needle aspiration cytology of lesions involving bone

Maisel

Frank

et al. 2017

Diagnostic Cytopathology

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“…But, definitive diagnosis is now considered possible since the cytomorphology of both benign and malignant bone tumors has now been described in detail in correlative cytological and histological studies and single monographs and reviews . One of the important reasons cited is the difficulty encountered in obtaining adequate material . Cytological reports of osteoblastoma have been rare.…”

Section: Discussionmentioning

confidence: 99%

“…19 One of the important reasons cited is the difficulty encountered in obtaining adequate material. 1 Cytological reports of osteoblastoma have been rare. The size and the expansile nature of these tumors are such that the surrounding cortex is frequently thinned to a narrow rim of bony sclerosis, which is penetrable by needles traditionally used for FNA.…”

Section: Discussionmentioning

confidence: 99%

“…Knowledge of the cytologic appearance of bone tumors is important because of the speed and low cost of diagnosing them by FNA and also because they may be inadvertently aspirated during the work‐up of a metastatic disease from which they can be distinguished. The accuracy of FNA in bone lesions can vary from 70 to 90% when the goal is to distinguish benign from malignant lesions; however, it is less accurate for precise sub‐classification of neoplasms . Spinal lesions with threatening cord compression are a medical emergency and FNA can rapidly issue a diagnosis.…”

mentioning

confidence: 99%

“…The accu-racy of FNA in bone lesions can vary from 70 to 90% when the goal is to distinguish benign from malignant lesions; however, it is less accurate for precise subclassification of neoplasms. 1 Spinal lesions with threatening cord compression are a medical emergency and FNA can rapidly issue a diagnosis. We report a case of an osteoblastoma of the cervical spine diagnosed primarily on FNA with review of literature.…”

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confidence: 99%

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Cytological diagnosis of osteoblastoma of cervical spine: A case report with review of literature

Venugopal

Prasad

2014

Diagnostic Cytopathology

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Osteoblastomas are rare benign but sometimes aggressive primary bone tumors (1%), usually seen in males in the 2nd decade. Osteoblastomas, occurring in the spine, constitute a medical emergency due to impending cord compression. Hence a rapid and simple diagnostic modality, such as fine-needle aspiration (FNA) plays an important role in clinical decision making. Cytological diagnosis of osteoblastoma is rare. We report a case of a young female patient presenting with a swelling in the left cervical paravertebral region. The X-ray findings were non-diagnostic and the patient was sent for an FNA. Aspiration yielded moderately cellular hemorrhagic smears with plasmacytoid cells, spindle cells, and osteoclastic giant cells in a background of matrix material. A diagnosis favoring osteoblastoma was made. The CT scan findings were in agreement with the cytological diagnosis and the lesion was excised. Histopathological examination confirmed the same. We describe here, the clinical and cytological features of osteoblastoma with their differential diagnosis, along with review of the literature. FNA can be used as an important tool in the pre-operative diagnosis of osteoblastoma.

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