Osteoblastomas are rare benign but sometimes aggressive primary bone tumors (1%), usually seen in males in the 2nd decade. Osteoblastomas, occurring in the spine, constitute a medical emergency due to impending cord compression. Hence a rapid and simple diagnostic modality, such as fine-needle aspiration (FNA) plays an important role in clinical decision making. Cytological diagnosis of osteoblastoma is rare. We report a case of a young female patient presenting with a swelling in the left cervical paravertebral region. The X-ray findings were non-diagnostic and the patient was sent for an FNA. Aspiration yielded moderately cellular hemorrhagic smears with plasmacytoid cells, spindle cells, and osteoclastic giant cells in a background of matrix material. A diagnosis favoring osteoblastoma was made. The CT scan findings were in agreement with the cytological diagnosis and the lesion was excised. Histopathological examination confirmed the same. We describe here, the clinical and cytological features of osteoblastoma with their differential diagnosis, along with review of the literature. FNA can be used as an important tool in the pre-operative diagnosis of osteoblastoma.
BACKGROUND AND OBJECTIVESThe wide variety of ovarian neoplasms makes it an interesting topic for study. The objectives of the present study was to study clinical and histopathologic features of various ovarian tumours and classify them according to WHO classification.
Background: Gastric cancer is the 2 nd leading cause of cancer related deaths worldwide as most of the patients present very late during the course of the disease due to non-specific symptoms. Aims: To study the gastric neoplasms with reference to the age and sex occurrence, endoscopic presentation and histomorphology. Settings and Design: Descriptive study Methods and Material: The present study included biopsies of patients with suspected gastric malignancy at Kempegowda Institute of Medical Sciences, Bangalore, from January 2003 to January 2011. Brief clinical data were collected. Sections studied were diagnosed as per W.H.O classification and The Revised Vienna Classification of Gastrointestinal Neoplasia and the presence of any associated lesions noted. Results: The study included 163 gastric biopsies of which 157 were neoplastic. There was a male predominance with a peak in the 5 th to 7 th decade. The commonest site of origin was antrum & prepylorus (59.87%) and commonest endoscopic presentation observed was ulcerative growth (62.42%). Of the 157 neoplasms, 153 (97.45%) were adenocarcinomas. The other 4 cases comprised of 2 cases of gastric carcinoid, one case each of gastric lymphoma and GIST. The associated findings noted were H. pylori infection (22.87% adenocarcinomas), chronic atrophic gastritis (23.52% adenocarcinomas), intestinal metaplasia (9.15% adenocarcinomas), fungal infection and a hyperplastic polyp. Of the 163 biopsies, majority were grouped under categories 4 and 5 (61.34% and 29.44% respectively) of The Revised Vienna classification. Conclusions: Endoscopy with assisted biopsy is the gold standard for diagnosis of gastric cancer. A team approach towards treatment involving the pathologist and clinicians becomes crucial.
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