Primary Ovarian Neoplasms: 5-Year Institutional Study

Modepalli, Nalini; Venugopal, Suguna Belur; Mukherjee, Tirthankar

doi:10.14260/jemds/2016/677

Cited by 3 publications

(7 citation statements)

References 7 publications

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“…Spectrum of surface epithelial ovarian tumorsAge of the patients in present study ranged from 18-90 years, with a mean of 47.56±14.88 years. This is comparable to the study conducted by Nalini5 et al in which the age ranged between 14 to 76 years with mean age being 42 years. Jha et al4 reported mean age of 53.35 years in their study of 86 patients with ovarian tumors.…”

supporting

confidence: 88%

Evaluation of surface epithelial ovarian tumors and its correlation with preoperative serum CA125 levels in a tertiary care centre

Sharma¹

2020

jmscr

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Introduction: Ovarian cancer is ranked third most frequent female cancer in India. The incidence varies between 2. 2 to 7. 8 per lakh population in various parts of India and there is steady increase in age standardized incidence rate of ovarian carcinoma. 1 The present study was aimed to evaluate the histomorphology of epithelial ovarian tumors and to find the relationship between serum CA-125 levels with histopathology and staging of these neoplasms. Material & Methods: 105 cases of surface epithelial ovarian tumors were evaluated over a period of one year from July 2018 to June 2019 in the Department of Pathology I.G.M.C Shimla. Preoperative serum CA125 levels were noted .Malignant tumors were staged using FIGO staging. Results: Serous tumors were the most common tumors reported in the study constituting 67 cases (63.8%). Benign tumors (64.76%) comprised the major group followed by malignant tumors (29.52%) and borderline tumors (5.7%).. Serum CA125 concentration in benign, borderline and malignant tumors were compared and statistically significant difference was found (p=0.000). CA125 showed positive correlation with the stage (p=0.024) of ovarian cancer. However no significant correlation was found between subtype of benign, borderline and malignant tumors with serum CA125 levels. Conclusion: Patients with borderline /malignant epithelial tumors had higher preoperative serum CA125 value as compared to benign ovarian tumors.

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confidence: 88%

Evaluation of surface epithelial ovarian tumors and its correlation with preoperative serum CA125 levels in a tertiary care centre

Sharma¹

2020

jmscr

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“…A wide variety of clinical, morphological, histopathological features are manifested in ovarian tumors that may be misdiagnosed for other neoplastic and non-neoplastic conditions. In the current study, incidence of benign tumors is 68% which is less than the incidence reported by Chandra and Arora, 6 Modepalli et al, 7 but more than that observed by Agrawal et al 4 similar to Valamarthy and Hema. 5 In the current study, benign tumors were common between 21 and 30 years of age (29.4%).…”

Section: Discussioncontrasting

confidence: 56%

“…Most ovarian tumors were unilateral which accounted for 85.3% benign and 78.5% malignant tumors. In the current study, epithelial tumors constituted 74% (37) of the cases followed by germ cell tumors 14% (7) as listed in Table 2.…”

Section: Resultsmentioning

confidence: 71%

“…A total of 42.8% of malignant tumors were seen in between 41 and 50 years which is comparable to Chandra and Arora 6 (31.6%) and Agrawal et al 4 (33.75%). In studies reported by Modepalli et al, 7 the peak incidence was between age group 21 and 30 (31%), 52.4% presented with mass per abdomen, and 33% cases had pain abdomen. In this study, 62% of ovarian tumors present with pain abdomen and 18% cases had mass per abdomen.…”

Section: Discussionmentioning

confidence: 85%

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Correlation of Clinical, Doppler Study and Histopathological Features of Ovarian Tumors

Kodali¹,

Shah²,

Sundari³

et al. 2022

Journal of South Asian Federation of Obstetrics and Gynaecology

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Aims and objectives:The aim of the study were: (1) to study the correlation between clinical, sonological, and histopathological features of ovarian tumors; (2) to assess accuracy, sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of color Doppler in differentiating benign and malignant ovarian pathologies; and (3) to study the epidemiology of ovarian tumors. Materials and methods: This is a prospective study conducted between March 2018 and September 2019. Inclusion criteria: All women who presented with adnexal masses (premenopausal: >5 cm, postmenopausal: any size) were included in this study. Exclusion criteria: Known case of ovarian tumors who came for second-look surgery. Anechoic unilocular cyst <5 cm in ovary that resolves on follow-up. Clinical presentation data such as age, parity, menstrual history, and per abdominal and per vaginal examination findings are collected. Ultrasound Doppler findings such as resistivity index (RI) and pulsatility index (PI) are calculated and correlated with histopathology postsurgery. Statistical analysis was done by Pearson's "R" correlation coefficient, sensitivity, specificity, accuracy, PPV, and NPV. Results: With RI (0.4) and PI (1), Doppler was able to differentiate 94.4% of the histopathological examination (HPE) benign cases and 97.1% of the HPE malignant cases. (Pearson's "R" for RI and HPE: 0.6925, Pearson's "R" for PI and HPE: 0.4215), the sensitivity and specificity of color Doppler 78.5 and 94.4%, respectively. The PPV was 84.6% and NPV was 91.8%. Diagnostic accuracy of color Doppler was 90.0%. Conclusion: Doppler with the prescribed RI and PI values has to be incorporated into screening of ovarian tumors as they have a high degree of sensitivity and specificity for malignant masses. Clinical significance: Doppler study is a cost-effective, noninvasive, diagnostic method and can be a useful tool for differentiating benign from malignant ovarian tumors.

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“…There is minimal literature regarding benign ovarian seromucinous neoplasms; this is mainly in the form of case reports or brief mention in studies of ovarian neoplasms in general, and in many of these detailed pathological descriptions are not available. 18,19,[21][22][23][24][25][26][27][28][29][30][31] Regarding studies of benign seromucinous neoplasms since the 2014 WHO publication, there have been two publications by Shamarkova et al 19 and Han et al, 18 which included seromucinous neoplasms in general. Neither of these studies described the pathological features in detail, and in fact in one of these studies the focus was on the radiological appearances.…”

Section: Discussionmentioning

confidence: 99%

Ovarian seromucinous cystadenomas and adenofibromas: first report of a case series

Ben-Mussa

McCluggage

2020

Histopathology

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Aims To report a series of benign ovarian seromucinous neoplasms, an uncommon and hitherto poorly described category of tumours included in the current 2014 World Health Organisation classification of tumours of the female reproductive organs. Methods and results We report the clinicopathological features of a series of 22 benign ovarian seromucinous neoplasms (cystadenomas and adenofibromas or admixtures). The neoplasms occurred in patients aged 32–83 years (mean = 62, median = 65.5) and involved the left ovary (n = 14), the right ovary (n = 6) or both ovaries (n = 2). There was a common association with endometrioid elements (endometrioid differentiation within the cystadenoma/adenofibroma and/or endometriosis) and other endometriosis‐associated neoplasms. Conclusions We speculate that some of these represent benign ovarian endometrioid neoplasms with foci of mucinous and/or serous differentiation, while others represent true mixed neoplasms.

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Primary Ovarian Neoplasms: 5-Year Institutional Study

Abstract: BACKGROUND AND OBJECTIVESThe wide variety of ovarian neoplasms makes it an interesting topic for study. The objectives of the present study was to study clinical and histopathologic features of various ovarian tumours and classify them according to WHO classification.

Cited by 3 publications

References 7 publications

Evaluation of surface epithelial ovarian tumors and its correlation with preoperative serum CA125 levels in a tertiary care centre

Evaluation of surface epithelial ovarian tumors and its correlation with preoperative serum CA125 levels in a tertiary care centre

Correlation of Clinical, Doppler Study and Histopathological Features of Ovarian Tumors

Ovarian seromucinous cystadenomas and adenofibromas: first report of a case series

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