Critical windows for maternal fine particulate matter exposure and adverse birth outcomes: The Shanghai birth cohort study

Yuan, Lei; Zhang, Yan; Wang, Weidong; Chen, Renjie; Liu, Yang; Liu, Cong; Kan, Haidong; Gao, Yu Tang; Tian, Ying

doi:10.1016/j.chemosphere.2019.124904

Cited by 67 publications

(22 citation statements)

References 60 publications

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“…Quantitively, 24 studies included, of which 11 studies assessed PTD and LBW [10,8,[11][12][13][14][15][16][17][18][19]. Five studies assessed LBW [6,[20][21][22][23] and eight studies assessed PTD [9,[24][25][26][27][28][29].…”

Section: Resultsmentioning

confidence: 99%

Air pollutants–particulate matter (PM)2.5 with antenatal exposure leading to adverse obstetrical outcomes of low birth weight and preterm birth: A systematic review and meta-analysis

Altangerel

Shih²,

Wang³

et al. 2023

International Surgery

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Introduction: PM 2.5 exposure impacts on prenatal health and birth outcomes including low birth weight and preterm delivery. Objective: To identify and explore PM 2.5 exposure on adverse obstetrical outcomes including preterm birth and low birth weight. Method: A total of 409 studies was identified by searching from PUBMED, EMBASE, SCOPUS, WEB OF SCIENCE, and SCIENCE DIRECT. Of the 409 articles from 1982 to 2020, 24 articles were identified qualitatively considered, and 7 articles were quantitively eligible included in this meta-analysis. The pooled effect of PM 2.5 exposure and LBW, PTD were calculated using a random effect model with significant heterogeneity.Totally, 7 studies conducted in meta-analysis, and the pooled effect of PM 2.5 exposure in LBW and entire pregnant were 1.033 (95%CI: 1.025, 1.041) with significant high heterogeneity (I 2 = 96.110, P=0.000). The pooled effect of PM 2.5 exposure PTD and entire pregnant were 1.024 (95%CI: 1.015, 1.033) with significant different low heterogeneity (I 2 = 60.036, P=0.082). Discussion: Although prenatal exposure of PM 2.5 during pregnancy is significantly associated with the risk of LBW, the risk of PTD is a significant differrent, but consistently associated with PM 2.5 . Conclusion: Globally, PM 2.5 exposure is significantly associated with serious outcomes of pregnancy and birth outcomes across the world. It appears in the prenatal health emerging risks that government is needed to influence the health policies to pursue on maternal and child health. Key words: “maternal”, “prenatal”, “air pollution”, “PM 2.5 ”, “Preterm Birth”, and ”Low Birth Weight.”

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Section: Resultsmentioning

confidence: 99%

Air pollutants–particulate matter (PM)2.5 with antenatal exposure leading to adverse obstetrical outcomes of low birth weight and preterm birth: A systematic review and meta-analysis

Altangerel

Shih²,

Wang³

et al. 2023

International Surgery

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“…Ballester et al [ 7 ] investigated a prospective birth cohort comprising 785 Spanish pregnant women and their newborns, and reported that NO 2 exposure in the first trimester reduced birth length by 0.27 cm (confidence interval (CI): −0.51 to −0.03) and birth weight by 40.3 g (CI: −96.3 to 15.6); the OR of SGA by weight and length were 1.37 to 1.42, respectively. [ 7 ] Based on their analysis of a live-birth cohort of 3692 Chinese study participants, Yuan et al [ 9 ] reported evidence that supported the previous findings that ambient air pollutants reduce birth weight and gestational length (preterm delivery (PTD)). They support that exposure to air pollutants in late pregnancy constitutes a crucial window of pollution exposure.…”

Section: Introductionmentioning

confidence: 82%

“…Thus, adverse pregnancy outcomes are important health indicators of neonatal and infant health. Exposure to toxicants during pregnancy has been linked to adverse pregnancy outcomes, which include shorter gestational duration [ 3 , 4 , 5 , 6 ] and fetal growth restriction [ 3 , 7 , 8 , 9 ]. Plausible mechanisms mediating the influence of toxicant exposure on a developing fetus may include impaired oxygen and nutrient transport to the fetus due to oxidative stress, inflammatory reactions, and hemodynamic changes because of prenatal exposure to air pollutants [ 10 , 11 ].…”

Section: Introductionmentioning

confidence: 99%

Influence of Environmental Tobacco Smoke and Air Pollution on Fetal Growth: A Prospective Study

Chen

Chiu

Yuan

et al. 2020

IJERPH

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Exposure to air pollution during pregnancy leads to adverse pregnancy outcomes. Few studies have evaluated the influences of air quality, including environmental tobacco smoke (ETS) and particulate matter (PM), on fetal development, which this study examined. This longitudinal correlation study used multiple linear regression data analysis of PM2.5/PM10, self-reported ETS exposure, urinary cotinine level, maternal characteristics, and birth parameters (gestational week, body weight, body length, head, and chest circumferences) with the effect of air quality on fetal growth. The study included 74 pregnant women (mean age 31.9 ± 4.2 years, body mass index 23.6 ± 3.8 kg/m2, average gestational duration 38.5 ± 0.8 weeks). ETS exposure decreased birth length by ≥1 cm, and potentially is an independent risk factor for fetal growth restriction, and pregnant women should avoid indoor and outdoor ETS. However, neither PM2.5/PM10 nor ETS was associated with low birth weight or small for gestational age. This study adds to the evidence base that ETS exposure of nonsmoking pregnant women affects the fetal birth length. Family members should refrain from smoking near expectant mothers, although smoking in the vicinity of their residential surroundings potentially exposes mothers and their fetuses to ETS. Public pollution and childbirth education classes should include details of indoor ETS.

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“…Similar to trimester-averaged exposure models, these studies have reported inconsistent findings and no clear etiologically relevant period of susceptibility has been identified. For example, studies have reported susceptible windows during both early and late gestation [31], early gestation only [32], middle gestation only [11], late gestation only [33], early and middle gestation [10], middle and late gestation [34], or have failed to identify any susceptible window [35,36]. A notable limitation of prior studies with high temporal resolution is that spatial resolution has been limited, with PM 2.5 exposure typically estimated at the zip code or county level using ground monitoring data.…”

Section: Discussionmentioning

confidence: 99%

Spatially and Temporally Resolved Ambient PM2.5 in Relation to Preterm Birth

Cowell

Colicino

Zhang

et al. 2021

Toxics

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Growing evidence suggests that maternal exposure to ambient fine particulate matter (PM2.5) during pregnancy is associated with preterm birth; however, few studies have examined critical windows of exposure, which can help elucidate underlying biologic mechanisms and inform public health messaging for limiting exposure. Participants included 891 mother–newborn pairs enrolled in a U.S.-based pregnancy cohort study. Daily residential PM2.5 concentrations at a 1 × 1 km2 resolution were estimated using a satellite-based hybrid model. Gestational age at birth was abstracted from electronic medical records and preterm birth (PTB) was defined as <37 completed weeks of gestation. We used Critical Window Variable Selection to examine weekly PM2.5 exposure in relation to the odds of PTB and examined sex-specific associations using stratified models. The mean ± standard deviation PM2.5 level averaged across pregnancy was 8.13 ± 1.10 µg/m3. PM2.5 exposure was not associated with an increased odds of PTB during any gestational week. In sex-stratified models, we observed a marginal increase in the odds of PTB with exposure occurring during gestational week 16 among female infants only. This study does not provide strong evidence supporting an association between weekly exposure to PM2.5 and preterm birth.

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Critical windows for maternal fine particulate matter exposure and adverse birth outcomes: The Shanghai birth cohort study

Cited by 67 publications

References 60 publications

Air pollutants–particulate matter (PM)2.5 with antenatal exposure leading to adverse obstetrical outcomes of low birth weight and preterm birth: A systematic review and meta-analysis

Air pollutants–particulate matter (PM)2.5 with antenatal exposure leading to adverse obstetrical outcomes of low birth weight and preterm birth: A systematic review and meta-analysis

Influence of Environmental Tobacco Smoke and Air Pollution on Fetal Growth: A Prospective Study

Spatially and Temporally Resolved Ambient PM2.5 in Relation to Preterm Birth

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