Crohn's disease in the over-60 age group

Héresbach, D.; Alexandre, Jean-Michel; Bretagne, Jean–François; Cruchant, E.; Dabadie, A.; Dartois-Hoguin, Michèle; Girardot, Pierre-Marie; Jouanolle, H.; Kerneis, J P; Verger, Jean-Claude Le; Louvain, Véronnique; Pennognon, Lena; Richecœur, M.; Politis, Joseph; Robaszkiewicz, Michel; Seyrig, J A; Tron, Isabelle

doi:10.1097/01.meg.0000108337.41221.08

Cited by 76 publications

(54 citation statements)

References 40 publications

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“…Similarly, comparable incidence rates for CD have been reported from France between 1994 and 1997 [47] . The annual incidence rate is 2.5/10 5 , with a higher proportion of colonic disease.…”

Section: Most Of the Published Data Come From The Unitedsupporting

confidence: 74%

Recent trends in the epidemiology of inflammatory bowel diseases: Up or down

Lakatos¹

2006

WJG

386

231

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Inflammatory bowel disease (IBD) is traditionally considered to be common in the Western world, and its incidence has sharply increased since the early 1950s. In contrast, until the last decade, low prevalence and incidence rates have been reported from other parts of the world including Eastern Europe, South America, Asia and the Pacific region. Recent trends indicate a change in the epidemiology of IBD with previously low incidence areas now reporting a progressive rise in the incidence, while in West European and North American countries the figures have stabilized or slightly increased, with decreasing incidence rates for ulcerative colitis. Some of these changes may represent differences in diagnostic practices and increasing awareness of the disease. The quality of studies is also variable. Additional epidemiologic studies are needed to better define the burden of illness, explore the mechanism of association with environmental factors, and identify new risk factors.

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Section: Most Of the Published Data Come From The Unitedsupporting

confidence: 74%

Recent trends in the epidemiology of inflammatory bowel diseases: Up or down

Lakatos¹

2006

WJG

386

231

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“…[25][26][27] Data on the disease course of EO IBD are mainly derived from small selected referral center cohorts, some collected decades ago. [28][29][30][31][32][33][34][35][36][37][38][39] Recent population-based data from the Hungarian registry and the French EPIMAD registry suggested a somewhat milder course of IBD diagnosed at older age, yet the number of elderly patients was limited 40 or data from the corresponding adult population were lacking, 41 impeding a direct comparison. To balance benefit and risk of treatment strategies in the elderly population, information on the current treatment strategy and disease outcome is needed, preferably from a large unselected population of patients with IBD studied in direct comparison to AO disease.…”

mentioning

confidence: 99%

Epidemiology and Long-term Outcome of Inflammatory Bowel Disease Diagnosed at Elderly Age—An Increasing Distinct Entity?

Jeuring

Heuvel

Zeegers

et al. 2016

Inflammatory Bowel Diseases

152

162

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“…Polymorphisms that have been reported to increase (308G/A) or decrease circulating TNF-␣ (238G/A, 857 C/T, 863 C/A) (27)(28)(29)(30)(31)(32)(33), as well as playing a possible role in disease phenotype and susceptibility (27)(28)(29)(30)(31)(32)(33)(34)(35)(36)(37)(38)(39). The 857C/T and 863C/A polymorphisms appear to be located at transcription factor binding sites (32,34,35).…”

mentioning

confidence: 99%