Cross-modal recognition disorders for persons and other unique entities in a patient with right fronto-temporal degeneration

Gainotti, Guido; Ferraccioli, Monica; Quaranta, Davide; Marra, Camillo

doi:10.1016/j.cortex.2006.09.001

Cited by 49 publications

(31 citation statements)

References 43 publications

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“…Even if we extend this list to include subjects in whom the data on face or voice discrimination is insufficient to exclude apperceptive deficits - e.g. Emma (Gentileschi et al, 2001), Maria (Gentileschi et al, 1999), CD (Gainotti et al, 2008) and case 31 (Neuner et al, 2000) – these two points still hold: mainly anterior temporal damage with either bilateral lesions or right dominant lesions with etiologies that cannot exclude a degree of bilaterality. Third, in functional neuroimaging of healthy subjects, temporal voice areas are found in the middle and anterior superior temporal sulci, and while these show right dominance, they are found bilaterally (Belin et al, 2000).…”

Section: Discussionmentioning

confidence: 99%

The processing of voice identity in developmental prosopagnosia

Liu

Corrow

Pancaroglu

et al. 2015

Cortex

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Background Developmental prosopagnosia is a disorder of face recognition that is believed to reflect impairments of visual mechanisms. However, voice recognition has rarely been evaluated in developmental prosopagnosia to clarify if it is modality-specific or part of a multi-modal person recognition syndrome. Objective Our goal was to examine whether voice discrimination and/or recognition are impaired in subjects with developmental prosopagnosia. Design/Methods 73 healthy controls and 12 subjects with developmental prosopagnosia performed a match-to-sample test of voice discrimination and a test of short-term voice familiarity, as well as a questionnaire about face and voice identification in daily life. Results Eleven subjects with developmental prosopagnosia scored within the normal range for voice discrimination and voice recognition. One was impaired on discrimination and borderline for recognition, with equivalent scores for face and voice recognition, despite being unaware of voice processing problems. Conclusions Most subjects with developmental prosopagnosia are not impaired in short-term voice familiarity, providing evidence that developmental prosopagnosia is usually a modality-specific disorder of face recognition. However, there may be heterogeneity, with a minority having additional voice processing deficits. Objective tests of voice recognition should be integrated into the diagnostic evaluation of this disorder to distinguish it from a multi-modal person recognition syndrome.

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Section: Discussionmentioning

confidence: 99%

The processing of voice identity in developmental prosopagnosia

Liu

Corrow

Pancaroglu

et al. 2015

Cortex

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“…25 Medial temporal lobe atrophy has similarly been reported in a subject with frontotemporal dementia and deficits in the recognition of familiar faces. 20 Functional MRI studies have also shown that the hippocampus and parahippocampal gyrus are activated during the recognition of famous faces, although the laterality of this activation varies. 22,[26][27][28] It has been suggested that the hippocampus (specifically the right hippocampus) plays a role with retrieving relevant information from semantic memory.…”

Section: Resultsmentioning

confidence: 99%

“…However, a number of case reports investigating subjects with acquired prosopagnosia have simi- larly shown atrophy in the right anterior inferior temporal lobe in these subjects. 7,[17][18][19][20] A longitudinal case report demonstrated that the onset of problems recognizing faces coincided with the development of atrophy in the right anterior temporal lobe 19 and it has been suggested that the anterior temporal region is involved with retrieval of biographical information. 21,22 The fusiform gyrus plays a central role in face processing, particularly in the perceptual analysis of faces, 21 and has been shown to be atrophic in subjects with prosopagnosia.…”

Section: Resultsmentioning

confidence: 99%

The anatomic correlate of prosopagnosia in semantic dementia

Josephs

Whitwell²,

Vemuri³

et al. 2008

Neurology

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Objective: To determine the anatomic correlate of prosopagnosia in subjects with semantic dementia. Methods:We identified all subjects who had been evaluated by an experienced behavioral neurologist, met criteria for semantic dementia, and had completed a volumetric head MRI scan. In all subjects, historical records were reviewed and subjects in which the presence (n ϭ 15) or absence (n ϭ 12) of prosopagnosia was specifically ascertained by the neurologist were identified. Voxel-based morphometry was used to assess patterns of gray matter atrophy in subjects with and without prosopagnosia compared to a group of age and gender-matched normal controls, and compared to each other. Results:Compared to controls, both groups showed prominent temporal lobe volume loss. Those with prosopagnosia showed bilateral loss but with greater involvement of the right temporal lobe, while those without prosopagnosia showed predominantly left anterior temporal lobe loss. On direct comparison, subjects with prosopagnosia showed greater loss predominantly in the right amygdala, hippocampus, fusiform gyrus, and anterior temporal pole than those without prosopagnosia. No regions were involved to a greater degree in those without prosopagnosia, compared to those with prosopagnosia.

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“…More sensitive may be tests of the ability to discriminate differences in facial structure introduced by altering features or their configuration (Barton, 2008; Liu, Pancaroglu, Hills, Duchaine, & Barton, 2014) or other match-to-sample tests, such as the Cambridge Face Perception Test (Bowles et al, 2009; Duchaine, Germine, & Nakayama, 2007). On occasion, tests of the perception of facial age, gender or gaze direction have been used as indices of perceptual encoding (Evans, Heggs, Antoun, & Hodges, 1995; Gainotti, Barbier, & Marra, 2003; Gainotti, Ferraccioli, Quaranta, & Marra, 2008; Gentileschi, Sperber, & Spinnler, 1999, 2001) but the logic of this strategy is dubious as these aspects are not directly related to facial identity, and in the case of age and gaze their perception likely depends on different cues (Lai, Oruc, & Barton, 2011) or even use different processing streams (Bruce & Young, 1986; Haxby et al, 2000). For voice encoding, similar discriminative tests have been created to assess matching of voices across different speech segments (Garrido et al, 2009; Hailstone et al, 2011; Liu et al, 2014; Neuner & Schweinberger, 2000; Van Lancker & Kreiman, 1987).…”

Section: Introductionmentioning

confidence: 99%

Recognizing and identifying people: A neuropsychological review

Barton

Corrow

2016

Cortex

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Recognizing people is a classic example of a cognitive function that involves multiple processing stages and parallel routes of information. Neuropsychological data have provided important evidence for models of this process, particularly from case reports; however, the quality and extent of the data varies widely between studies. In this review we first discuss the requirements and logical basis of the types of neuropsychological evidence to support conclusions about the modules in this process. We then survey the adequacy of the current body of reports to address two key issues. First is the question of which cognitive operation generates a sense of familiarity: the current debate revolves around whether familiarity arises in modality-specific recognition units or later amodal processes. Key evidence on this point comes from the search for dissociations between familiarity for faces, voices and names. The second question is whether lesions can differentially affect the abilities to link diverse sources of person information (e.g. face, voice, name, biographic data). Dissociations of these linkages may favour a distributed-only model of the organization of semantic knowledge, whereas a ‘person-hub’ model would predict uniform impairments of all linkages. While we conclude that there is reasonable evidence for dissociations in name, voice and face familiarity in regards to the first question, the evidence for or against dissociated linkages between information stores in regards to the second is tenuous at best. We identify deficiencies in the current literature that should motivate and inform the design of future studies.

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Cross-modal recognition disorders for persons and other unique entities in a patient with right fronto-temporal degeneration

Cited by 49 publications

References 43 publications

The processing of voice identity in developmental prosopagnosia

The processing of voice identity in developmental prosopagnosia

The anatomic correlate of prosopagnosia in semantic dementia

Recognizing and identifying people: A neuropsychological review

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