Cross-reacting antibodies to Sarcoptes suis, Chorioptes bovis and Notoedres cati and anti-P. ovis IgE in sera from sheep infested naturally with Psoroptes ovis

Matthes, H.-F.; Harrison, G.B.L.; Shaw, R.J.; Heath, Allen; Pfeffer, A.; Hiepe, Theodor

doi:10.1016/0020-7519(96)00005-7

Cited by 17 publications

(10 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…ovis titres in sheep which had been vaccinated against Lucilia cuprina (Wiedemann). Cross reactivity among insects in antibody response has also been demonstrated in other studies (Mock, 1974;Jones & Lloyd, 1987;Baldo & Panzani, 1988;Matthes et al, 1996). Stable flies and mosquitoes were present in the sheep barn in the summer in both years, although not in high numbers, and it is likely that the ewes had been exposed to other insects before they were purchased for this study.…”

Section: Discussionsupporting

confidence: 77%

“…This may suggest that qualitative rather than quantitative differences in the secreted antibodies are important. Matthes et al (1996) found that serum from sheep infested with Psoroptes ovis (Hering) recognized twenty-four different antigens from P. ovis. A similar wide range of antigens is likely in B. ovis and any one of these may be important.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Serum and skin surface antibodies and their associations with sheep biting lice, Bovicola ovis, on experimentally infested sheep

James

Moon

Ragsdale

1998

Medical Vet Entomology

View full text Add to dashboard Cite

The sheep biting louse (Bovicola ovis) feeds superficially on the skin of sheep but appears to stimulate an immune response. In this study we examined the association between louse infestation and serum and skin surface antibodies. Louse numbers were monitored on experimentally infested Polypay and Columbia ewes for two years and on their lambs in the second year. Serum and skin wash samples were tested for antibodies to soluble extracts of B. ovis, Stomoxys calcitrans and Musca autumnalis by enzyme linked immunosorbent assay (ELISA). In addition, the effects of skin wash extracts on B. ovis were examined in vitro. The titre of anti-B. ovis antibodies in the serum did not differ significantly between infested and naive ewes. However, there was an increase in serum antibody titre which coincided with periods of high louse density in ewes with high louse counts. Infested lambs had higher serum antibody levels than naive lambs. Substantial cross reactivity was evident among extracts of the different insects. Densities of lice on the ewes during population decline were negatively related to the titre of skin surface antibodies. Skin washings collected from sheep during B. ovis population decline reduced the number of louse progeny when incorporated into louse diet. These results indicate that B. ovis stimulates an immune response in sheep and suggest that compounds on the skin surface may play a role in the regulation of louse populations.

show abstract

Section: Discussionsupporting

confidence: 77%

Section: Discussionmentioning

confidence: 99%

Serum and skin surface antibodies and their associations with sheep biting lice, Bovicola ovis, on experimentally infested sheep

James

Moon

Ragsdale

1998

Medical Vet Entomology

View full text Add to dashboard Cite

show abstract

“…Various workers have earlier indicated an adverse effect of psoroptic mange on the immune system of sheep (Fisher, 1972; Boyce and Zarnke, 1996; Matthes et al., 1996; Ochs et al., 2001; Kenyon and Knox, 2002) and cattle (Losson et al., 1988; Uhlir, 1989) but no report could be traced with detailed effect of sarcoptic mange on CMI and HI responses in sheep. The present work indicated an adverse effect of infection on both cell‐mediated and humoral immunity.…”

Section: Discussionmentioning

confidence: 99%

Effects of Sarcoptic Mange and its Control with Oil of Cedrus deodara, Pongamia glabra, Jatropha curcas and Benzyl Benzoate, both with and without Ascorbic Acid on Growing Sheep: Epidemiology; Assessment of Clinical, Haematological, Cell‐Mediated Humoral Immune Responses and Pathology

Dimri

Sharma²

2004

Journal of Veterinary Medicine Series A

View full text Add to dashboard Cite

The aim of this study was to evaluate the therapeutic efficacy of commonly used acaricidal drugs in India and also to assess the effect of ascorbic acid (AA) as adjunct therapy in 72 growing sheep with sarcoptic mange, aged 5-6 months and weighing 20.4-31.7 kg. Eight replicates of nine animals were formed based on sex, and day 0 body weight. Another set of 12 healthy sheep (5-6 months old) constituted the healthy control group. Drugs were applied locally on the affected parts daily and recovery changes in skin lesions were observed at the time of every application. L-Ascorbic acid was administered intramuscularly. Skin scrapings were collected daily from each group and examined for the presence of mites. Blood samples from each group were collected and analysed for total erythrocytes, leucocytes, haematocrit, haemoglobin and lymphocytes on 0, 14th and 28th day post-treatment (PT). Cell-mediated (CMI) and humoral immune (HI) responses were assessed on 0 and 28 days PT. Within groups treated with the drug alone, recovery in oil of Jatropha curcas group was faster and lesions were free from mites after the eighth application. For each drug, the recovery was faster with AA as an adjunct therapy when compared with the group treated with the drug alone. Within all groups, recovery in oil of J. curcas plus ascorbic acid (OJC-AA) group was fastest and the lesions were mite-free after three applications. The overall mean values were higher for all haematological parameters in OJC-AA group. Recovery with respect to suppressed CMI and HI responses during infection was also faster in this group. Gross and microscopic pathological studies revealed a marked adverse effect of infection on skin, kidney, spleen and liver. The OJC-AA group indicated faster recovery. It is concluded from this study that oil of J. curcas was found more efficacious in controlling sarcoptic mange in sheep and AA might be beneficial as adjunct in case of sarcoptic mange to get quick recovery with lesser applications of main therapy. However, the pharmacology of AA with reference to health of skin needs to be investigated.

show abstract

“…ovis antigen-speci®c immunoglobulin IgG but not IgE antibody titres have been monitored in primary infestations of sheep (O'Brien 1992, Bates 1997. However, lesional histopathology of naturally occurring infestations of sheep has revealed a pronounced eosinophil in®ltrate (Rovere & Nunez 1977, Rosa & Moschini 1988) and sodium dodecyl sulphate-polyacrylamide gel electrophoresis/Western blot studies (Matthes et al 1996) have demonstrated the presence of P. ovis antigen-speci®c IgE antibody in sera from infested sheep and deer. These observations are consistent with the participation of immediate hypersensitivity in the immunopathogenesis of cutaneous lesions but give no indication of its role in protective immunity.…”

Section: Introductionmentioning

confidence: 99%

Cutaneous and systemic responses during primary and challenge infestations of sheep with the sheep scab mite, Psoroptes ovis

Broek

Huntley

Machell

et al. 2000

Parasite Immunology

View full text Add to dashboard Cite

Lesional area was estimated and lesional mast cells and eosinophils were counted during primary and challenge infestations of sheep with Psoroptes ovis. In addition, circulating basophils and eosinophils and serum P. ovis-specific immunoglobulin IgE antibody were quantified. Expansion of lesional area was significantly less and serum IgE titres significantly greater in challenge than primary infestations. Lesional mast cell hyperplasia and massive eosinophil infiltration accompanied by raised titres of P. ovis antigen-specific IgE antibody were compatible with an IgE-mediated Type-1 allergic reaction, while detection of lesional basophils was suggestive of cutaneous basophil hypersensitivity. The temporal pattern of lesional mastocytosis and eosinophil infiltration and the role of these cells and serum IgE in the immune response is discussed.

show abstract

Cross-reacting antibodies to Sarcoptes suis, Chorioptes bovis and Notoedres cati and anti-P. ovis IgE in sera from sheep infested naturally with Psoroptes ovis

Cited by 17 publications

References 22 publications

Serum and skin surface antibodies and their associations with sheep biting lice, Bovicola ovis, on experimentally infested sheep

Serum and skin surface antibodies and their associations with sheep biting lice, Bovicola ovis, on experimentally infested sheep

Effects of Sarcoptic Mange and its Control with Oil of Cedrus deodara, Pongamia glabra, Jatropha curcas and Benzyl Benzoate, both with and without Ascorbic Acid on Growing Sheep: Epidemiology; Assessment of Clinical, Haematological, Cell‐Mediated Humoral Immune Responses and Pathology

Cutaneous and systemic responses during primary and challenge infestations of sheep with the sheep scab mite, Psoroptes ovis

Contact Info

Product

Resources

About